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鉴定小分子药物的靶蛋白对于理解药物的作用机理以及药物副作用至关重要。传统方法需要对药物进行化学修饰共价交联，可能会导致药物活性的改变。目前已经发展多种无需化学修饰便可以对药物靶蛋白鉴定的方法，包括药物亲和力反应靶标稳定性技术 (Drug affinity responsive target stability，DARTS)、蛋白质氧化速率稳定性技术 (Stability of proteins from rates of oxidation，SPROX)、细胞热移位分析...鉴定小分子药物的靶蛋白对于理解药物的作用机理以及药物副作用至关重要。传统方法需要对药物进行化学修饰共价交联，可能会导致药物活性的改变。目前已经发展多种无需化学修饰便可以对药物靶蛋白鉴定的方法，包括药物亲和力反应靶标稳定性技术 (Drug affinity responsive target stability，DARTS)、蛋白质氧化速率稳定性技术 (Stability of proteins from rates of oxidation，SPROX)、细胞热移位分析...
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Brown Adipose Tissue and Its Role in Insulin and Glucose Homeostasis棕色脂肪组织及其在胰岛素与葡萄糖稳态中的作用
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Single-administration, thermostable human papillomavirus vaccines prepared with atomic layer deposition technology单次给药、采用原子层沉积技术制备的热稳定型人乳头瘤病毒疫苗
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New GMP manufacturing processes to obtain thermostable HIV-1 gp41 virosomes under solid forms for various mucosal vaccination routes新型GMP生产工艺制备固态热稳定HIV-1 gp41病毒体用于多种黏膜疫苗接种途径
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Incorporating natural anti-inflammatory compounds into yeast glucan particles increases their bioactivity in vitro.将天然抗炎化合物纳入酵母β-葡聚糖颗粒中可提高其体外生物活性
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Development of a formulation platform for a spray-dried, inhalable tuberculosis vaccine candidate.开发一种用于喷雾干燥可吸入结核病疫苗候选物的制剂平台。
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Recent advances in identifying protein targets in drug discovery.药物发现中识别蛋白靶标的最新进展
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Approaches for enhancing the stability and formation of sulforaphane.提高萝卜硫素稳定性与生成的方法
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Nutritional manipulation to combat heat stress in poultry - A comprehensive review.通过营养调控缓解家禽热应激——综述
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Identification of Stability Constraints in the Particle Engineering of an Inhaled Monoclonal Antibody Dried Powder.吸入型单克隆抗体干粉颗粒工程中的稳定性约束识别
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Local Treatment of Non-small Cell Lung Cancer with a Spray-Dried Bevacizumab Formulation喷雾干燥贝伐珠单抗制剂局部治疗非小细胞肺癌
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Supplementation of Diets With Bovine Colostrum Influences Immune and Gut Function in Kittens日粮中添加牛初乳对幼猫免疫与肠道功能的影响
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Tolerance mechanisms for breeding wheat against heat stress: A review耐热小麦育种耐受机制综述
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Electrostatic spray drying for monoclonal antibody formulation.单克隆抗体制剂的静电喷雾干燥
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Heat Stress in Cotton: A Review on Predicted and Unpredicted Growth-Yield Anomalies and Mitigating Breeding Strategies棉花热应激：预测与非预测生长-产量异常及缓解育种策略综述
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Chaperone Networks in Fungal Pathogens of Humans人类真菌病原体中的伴侣网络
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Comparing freeze drying and spray drying of interleukins using model protein CXCL8 and its variants使用模型蛋白CXCL8及其变体比较白细胞介素的冷冻干燥与喷雾干燥
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Unconventional β-Glucosidases: A Promising Biocatalyst for Industrial Biotechnology.非常规β-葡萄糖苷酶：工业生物技术中的有前景的生物催化剂
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Recent developments in natural products for white adipose tissue browning.天然产物诱导白色脂肪组织褐变的研究进展
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New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: a decade review (2011–2021) focussing on structure–activity relationship (SAR) and docking insights淋巴细胞特异性蛋白酪氨酸激酶（Lck）抑制剂药物研发新进展：十年回顾（2011–2021）——聚焦构效关系（SAR）与分子对接研究