Nutritional manipulation to combat heat stress in poultry - A comprehensive review.

✅ 全文

通过营养调控缓解家禽热应激——综述

作者 A. E. Abdel-Moneim; Abdelrazeq M. Shehata; Raafat E. Khidr; V. Paswan; N. S. Ibrahim; Abdelkawy A. El-Ghoul; S. A. Aldhumri; S. Gabr; Noura M. Mesalam; A. Elbaz; M. Elsayed; M. Wakwak; T. Ebeid 期刊 Journal of thermal biology 发表日期 2021 DOI 10.1016/j.jtherbio.2021.102915 类型 原创研究 (Original Research)

📄 英文摘要 English Abstract

EN

Global warming and climate change adversely affect livestock and poultry production sectors under tropical and subtropical conditions. Heat stress is amongst the most significant stressors influencing poultry productivity in hot climate regions, causing substantial economic losses in poultry industry. These economic losses are speculated to increase in the coming years with the rise of global temperature. Moreover, modern poultry strains are more susceptible to high ambient temperature. Heat stress has negative effects on physiological response, growth performance and laying performance, which appeared in the form of reducing feed consumption, body weight gain, egg production, feed efficiency, meat quality, egg quality and immune response. Numerous practical procedures were used to ameliorate the negative impacts of increased temperature; among them the dietary manipulation, which gains a great concern in different regions around the world. These nutritional manipulations are feed additives (natural antioxidants, minerals, electrolytes, phytobiotics, probiotics, fat, and protein), feed restriction, feed form, drinking cold water and others. However, in the large scale of poultry industry, only a few of these strategies are commonly used. The current review article deliberates the different practical applications of useful nutritional manipulations to mitigate the heat load in poultry. The documented information will be useful to poultry producers to improve the general health status and productivity of heat-stressed birds via enhancing stress tolerance, oxidative status and immune response, and thereby provide recommendations to minimize production losses due to heat stress in particular under the growing global warming crisis.

📄 中文摘要 Chinese Abstract

中文
高温环境对家禽存活率、生产性能和产品质量的不利影响已被广泛记录,给众多农业企业带来了持续的经济挑战。热应激家禽表现为采食量下降,同时体成分发生变化,特征为脂质沉积增加和肌肉中蛋白质含量降低。热应激会诱导大量自由基的产生,损害肉质和动物健康,同时伴随酸中毒,导致肌肉持水力下降,影响肉质纹理并扰乱营养转运蛋白的表达。通过在现代家禽养殖场维持适当的温度和湿度等有效管理措施可以缓解热应激;然而,这些方法成本高昂,增加了生产成本,且在发展中国家的许多地区仍难以实现。在动物日粮中补充铬(Cr)作为热应激缓解剂在畜牧业中日益受到重视。铬可以无机或有机形式添加于日粮中,有机形式包括丙酸铬、吡啶甲酸铬、蛋氨酸铬和酵母铬。铬通过胰岛素信号通路在碳水化合物、蛋白质和脂质代谢中发挥关键作用,增强家禽骨骼肌中氨基酸和葡萄糖的吸收。

📋 英文结构化总结 English Structured Summary

全文整理

EN

**Header: Background** The adverse impacts of high ambient temperatures on poultry survival, performance, and product quality are extensively documented, presenting ongoing economic challenges for many agricultural enterprises. Heat-stressed poultry exhibit reduced feed intake, accompanied by changes in body composition characterized by heightened lipid deposition and diminished protein content in the muscle. Thermal stress induces high production of free radicals, compromising the meat quality and animal health, alongside acidosis, which reduces meat water-holding capacity, impairing its texture and disrupting nutrient transporter expression. Effective management practices involving the maintenance of appropriate temperature and humidity in modern poultry farms can mitigate heat stress; however, such approaches are costly, increasing production expenses, and remain inaccessible for many regions in developing countries. Chromium (Cr) supplementation in animal diets is gaining importance in livestock farming as a heat stress alleviator. Cr can be administered in diets as either inorganic or organic forms, with organic forms including Cr propionate, Cr picolinate, Cr methionine, and Cr yeast. Cr plays a crucial role in carbohydrates, protein, and lipid metabolism through insulin signalling, enhancing amino acid and glucose absorption in poultry skeletal muscles.

**Header: Methods** A total of 245 as-hatched, 1 d old broiler chickens were randomly assigned to seven treatments, each with seven replicates of five birds. The control group received a basal diet without Cr supplementation. In the six other groups, chickens were fed a basal diet supplemented with 100, 200, and 400 ppb of organic and inorganic Cr. From days 25 to 42 d of age, the birds were subjected to heat stress for 3 consecutive days per week. The study investigated the effect of supplementation with various levels of inorganic and organic Cr on productive performance, nutrient digestibility, and meat quality in broiler chickens subjected to cyclic heat stress.

**Header: Results** Within chromium-supplemented treatments, the interaction between source and level of Cr influenced body weight gain (BWG) and feed conversion ratio (FCR) (P<0.01), with the best values obtained at 400 ppb of organic Cr and 100 ppb of inorganic Cr. Dietary supplementation with organic Cr resulted in higher apparent digestibility (AD) of organic matter (OM; P<0.05) and crude protein (CP; P<0.01), while Cr levels (P<0.01) affected AD of OM, CP, and ether extract (EE), with the best values observed at 200 and 400 ppb of Cr. Supplementation with 400 ppb of organic Cr or 100 ppb of inorganic Cr improved the growth performance and nutrient digestibility of broiler chickens raised under heat stress conditions.

**Header: Data Summary** Key quantitative findings include a significant interaction between Cr source and level for BWG and FCR (P<0.01), with optimal performance at 400 ppb organic Cr and 100 ppb inorganic Cr. Organic Cr supplementation significantly increased apparent digestibility of OM (P<0.05) and CP (P<0.01). Chromium levels significantly affected AD of OM, CP, and EE (P<0.01), with best values at 200 and 400 ppb. These results demonstrate dose- and source-dependent effects of Cr under cyclic heat stress.

**Header: Conclusions** Supplementation with 400 ppb of organic Cr or 100 ppb of inorganic Cr improved the growth performance and nutrient digestibility of broiler chickens raised under heat stress conditions. These findings align with the objective of the study and support the use of source-specific chromium supplementation strategies to mitigate cyclic heat stress in broilers.

**Header: Practical Significance** The study provides evidence that targeted chromium supplementation—specifically 400 ppb organic or 100 ppb inorganic Cr—can enhance broiler performance and nutrient utilization under cyclic heat stress, offering a cost-effective alternative to expensive environmental control measures. This approach is particularly relevant for regions in developing countries where maintaining optimal temperature and humidity in poultry farms remains inaccessible, thereby supporting sustainable poultry production under challenging climatic conditions.

📋 中文结构化总结 Chinese Structured Summary

中文

背景:

高温环境对家禽存活率、生产性能和产品质量的不利影响已被广泛记录,给众多农业企业带来了持续的经济挑战。热应激家禽表现为采食量下降,同时体成分发生变化,特征为脂质沉积增加和肌肉中蛋白质含量降低。热应激会诱导大量自由基的产生,损害肉质和动物健康,同时伴随酸中毒,导致肌肉持水力下降,影响肉质纹理并扰乱营养转运蛋白的表达。通过在现代家禽养殖场维持适当的温度和湿度等有效管理措施可以缓解热应激;然而,这些方法成本高昂,增加了生产成本,且在发展中国家的许多地区仍难以实现。在动物日粮中补充铬(Cr)作为热应激缓解剂在畜牧业中日益受到重视。铬可以无机或有机形式添加于日粮中,有机形式包括丙酸铬、吡啶甲酸铬、蛋氨酸铬和酵母铬。铬通过胰岛素信号通路在碳水化合物、蛋白质和脂质代谢中发挥关键作用,增强家禽骨骼肌中氨基酸和葡萄糖的吸收。

方法:

共选取245只1日龄刚出壳的肉仔鸡,随机分为7个处理组,每个处理组设7个重复,每个重复5只鸡。对照组饲喂不添加铬的基础日粮。其余6个处理组分别饲喂在基础日粮中添加100、200和400 ppb有机铬或无机铬的日粮。从25日龄至42日龄,每周连续3天对家禽施加热应激处理。本研究旨在探讨在循环热应激条件下,补充不同水平的无机铬和有机铬对肉仔鸡生产性能、营养物质消化率和肉质的影响。

结果:

在铬补充处理中,铬来源与水平之间的交互作用显著影响体增重(BWG)和料肉比(FCR)(P<0.01),其中400 ppb有机铬和100 ppb无机铬处理组获得最佳值。日粮补充有机铬显著提高了有机物(OM)的表观消化率(AD)(P<0.05)和粗蛋白(CP)的表观消化率(P<0.01),而铬水平显著影响了OM、CP和粗脂肪(EE)的表观消化率(P<0.01),其中200和400 ppb铬处理组获得最佳值。补充400 ppb有机铬或100 ppb无机铬可改善热应激条件下肉仔鸡的生长性能和营养物质消化率。

数据总结:

关键定量结果包括:铬来源与水平之间对BWG和FCR存在显著交互作用(P<0.01),在400 ppb有机铬和100 ppb无机铬时获得最佳生产性能。有机铬补充显著提高了OM(P<0.05)和CP(P<0.01)的表观消化率。铬水平显著影响OM、CP和EE的表观消化率(P<0.01),在200和400 ppb时获得最佳值。这些结果表明,在循环热应激条件下,铬的作用具有剂量依赖性和来源依赖性。

结论:

补充400 ppb有机铬或100 ppb无机铬可改善热应激条件下肉仔鸡的生长性能和营养物质消化率。这些发现与研究目标一致,支持采用特定来源的铬补充策略来缓解肉仔鸡的循环热应激。

实践意义:

本研究提供了证据,表明有针对性的铬补充——特别是400 ppb有机铬或100 ppb无机铬——可在循环热应激条件下提高肉仔鸡的生产性能和营养物质利用率,为昂贵的环境控制措施提供了一种经济有效的替代方案。这一方法对于在发展中国家维持家禽养殖场最佳温度和湿度仍难以实现的地区尤为重要,从而支持在具有挑战性的气候条件下实现可持续的家禽生产。

📖 英文全文 English Full Text

EN

Open Access Archives Animal Breeding

Enhancement of productive performance, nutrient digestibility, and meat quality in broilers subjected to cyclic heat stress via different organic and inorganic chromium concentrations Youssef Abdelwahab Attia1 , Nicola Francesco Addeo2 , Fulvia Bovera2 , Rashed Abdullah Alhotan3 , Khalid Ali Asiry1 , Mohamed Alsaeed Al-Banoby4 , El-Shahat Mohamed Qota5 , Adel Daifallah Al-qurashi1 , and Ahmed Shaban Awad6 1 Sustainable Agriculture Research Group, Agriculture Department, Faculty of Environmental Sciences,

King Abdulaziz University, Jeddah 21589, Saudi Arabia 2 Sustainable Agriculture Research Group, Department of Veterinary Medicine and Animal Production,

University of Napoli Federico II, via F. Delpino,1, 80137, Napoli, Italy 3 Department of Animal Production, College of Food and Agricultural Sciences,

King Saud University, Riyadh 11451, Saudi Arabia 4 Al-Shamel Animal Feed Factory, Industrial Area, Hail 55411, Saudi Arabia 5 Department of Poultry Nutrition, Animal Production Research Institute, Agriculture Research Center,

Ministry of Agriculture, Dokki, Giza, Egypt 6 Rabbits, Turkey and waterfowl Department, Animal Production Research Institute,

Agriculture Research Center, Ministry of Agriculture, Dokki, Giza, Egypt Correspondence: Youssef Abdelwahab Attia (yaattia@kau.edu.sa), Nicola Francesco Addeo (nicolafrancesco.addeo@unina.it), Fulvia Bovera (bovera@unina.it), and Rashed Abdullah Alhotan (ralhotan@ksu.edu.sa) Received: 8 November 2024 – Revised: 8 January 2026 – Accepted: 15 January 2026 – Published: 28 April 2026

Abstract. Dietary chromium (Cr) supplementation of chickens may be a tool to reduce heat stress and its asso-

ciated consequences. This study aims to investigate the effect of supplementation with various levels of inorganic and organic Cr on productive performance, nutrient digestibility, and meat quality in broiler chickens subjected to cyclic heat stress. A total of 245 as-hatched, 1 d old broiler chickens were randomly assigned to seven treatments, each with seven replicates of five birds. The control group received a basal diet without Cr supplementation. In the six other groups, chickens were fed a basal diet supplemented with 100, 200, and 400 ppb of organic and inorganic Cr. From days 25 to 42 d of age, the birds were subjected to heat stress for 3 consecutive days per week. Within chromium-supplemented treatments, the interaction between source and level of Cr influenced body weight gain (BWG) and feed conversion ratio (FCR) (P <0.01), with the best values obtained at 400 ppb of organic Cr and 100 ppb of inorganic Cr. Dietary supplementation with organic Cr resulted in higher apparent digestibility (AD) of organic matter (OM; P <0.05) and crude protein (CP; P <0.01), while Cr levels (P <0.01) affected AD of OM, CP, and ether extract (EE), with the best values observed at 200 and 400 ppb of Cr. Supplementation with 400 ppb of organic Cr or 100 ppb of inorganic Cr improved the growth performance and nutrient digestibility of broiler chickens raised under heat stress conditions. These findings align with the objective of the study and support the use of source-specific chromium supplementation strategies to mitigate cyclic heat stress in broilers.

Published by Copernicus Publications on behalf of the Research Institute for Farm Animal Biology (FBN). Original study

Arch. Anim. Breed., 69, 251–263, 2026 https://doi.org/10.5194/aab-69-251-2026 © Author(s) 2026. This work is distributed under the Creative Commons Attribution 4.0 License. 252 1

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers Introduction

The adverse impacts of high ambient temperatures on poultry survival, performance, and product quality are extensively documented, presenting ongoing economic challenges for many agricultural enterprises. Heat-stressed poultry exhibit reduced feed intake, accompanied by changes in body composition characterized by heightened lipid deposition and diminished protein content in the muscle (Abdel-Moneim et al., 2021). Thermal stress induces high production of free radicals, compromising the meat quality and animal health, alongside acidosis, which reduces meat water-holding capacity, impairing its texture (Nawaz et al., 2021) and disrupting nutrient transporter expression (Orhan et al., 2019). Effective management practices involving the maintenance of appropriate temperature and humidity in modern poultry farms can mitigate heat stress (Saleh et al., 2023). However, such approaches are costly, increasing production expenses, and remain inaccessible for many regions in developing countries (Nawab et al., 2018). Chromium (Cr) supplementation in animal diets is gaining importance in livestock farming as a heat stress alleviator (Shan et al., 2020; Wang et al., 2023; Dalólio et al., 2024; Apalowo et al., 2024). Cr supplementation at 1 mg kg−1 or at 0.687 mg kg−1 has been recommended to mitigate the detrimental effects of heat stress in poultry by Piray and Foroutanifar (2021) and Kim et al. (2023), respectively, irrespective of the Cr source. Cr can be administered in diets as either inorganic or organic forms. Four forms of organic Cr are commercially available: Cr propionate, Cr picolinate, Cr methionine, and Cr yeast. Chromium picolinate, approved by the FDA for veterinary use in 1996, was introduced first (Chandrasekar and Balakrishnan, 2019). Cr plays a crucial role in carbohydrates, protein, and lipid metabolism through insulin signalling, enhancing amino acid and glucose absorption in poultry skeletal muscles (Chandrasekar and Balakrishnan, 2019). Additionally, Cr activates insulin receptors and mobilizes glucose transporter type 4 (GLUT 4) to improve glucose uptake (Vincent, 2015), potentially enhancing nutrient utilization and production performance. However, the effects of Cr supplementation on broiler chicken production remain contentious. While some studies indicate potential improvements in productivity and carcass characteristics (Huang et al., 2016; Lu et al., 2019; Hayat et al., 2020; Dalólio et al., 2021; Youssef et al., 2022; Fraz et al., 2023), others report no significant effects (Lee et al., 2003; Souza et al., 2010; Kim et al., 2021). Orhan et al. (2019) showed improved nutrient digestibility in hens supplemented with chromium picolinate or chromium histidinate, underscoring the trace element’s importance in poultry nutrition through increased nutrient transporter expression. The regulatory status of chromium (Cr) as a feed additive varies across different geographical regions. In the European Union, chromium is not authorized as a general nutritional additive; however, specific chromium compounds may be permitted only following a scientific assessment by the EuArch. Anim. Breed., 69, 251–263, 2026

ropean Food Safety Authority (EFSA) and formal authorization under regulation (EC) no. 1831/2003 for defined animal species and inclusion levels. In the United States, chromium propionate is approved by the Food and Drug Administration (FDA) as a feed additive for food-producing animals, including poultry, under specific conditions of use and maximum inclusion limits. In Saudi Arabia, the use of chromiumcontaining feed additives is subject to product-specific registration and approval by the relevant competent authorities, and no general authorization for chromium as a feed additive is publicly available. This study aims to compare the efficacy of organic and inorganic chromium at various concentrations in alleviating the effects of heat stress on broiler chickens, providing a comprehensive study of their impact on growing performance. Additionally, the research contributes to identifying the optimal dosages of both organic and inorganic chromium to maximize productivity and nutrient digestibility in broilers exposed to heat stress. Finally, this research contributes to existing literature on different chromium sources, offering detailed insights into their effects on specific nutrient digestibility and enhancing nutritional management of heat-stressed poultry.

A total of 245 Cobb500 broiler chicks (1 d old, both sexes) were wing-banded and randomly distributed based on similar initial body weight in a completely randomized design with seven treatments, each including seven replicates of five chicks. The sample size was chosen for logistical management reasons while maintaining an adequate number of replicates to obtain statistical power and minimize the effect of chance on the results. The choice of seven treatments reflects the desire to examine both the response to the presence or absence of chromium and the effects of specific concentrations of each source as efficiently as possible. The inclusion of a chromium-unsupplemented control group allows for a clear comparison with the organic and inorganic chromium treatments while maintaining the power of the experiment with a simple design. This approach allows us to isolate the main effect of different chromium concentrations and answer our hypothesis. Each replicate was maintained in a battery brooder (metal cage) with a size of 35 cm × 25 cm × 30 cm (L × W × H). The negative control group was fed a basal diet without Cr supplementation. In the six other groups, chicks were fed the same basal diet supplemented with 100, 200, and 400 ppb of organic (Cr picolinate, C18H12N3O6Cr; Nowfoods.com, made in Canada and quality tested in Bloomingdale, IL, USA) and inorganic Cr (Cr chloride, CrCl3; Muby Chemicals of the Mubychem Group, Mubychem, western India). The Cr content of the diets was determined using a Varian 720-ES ICP–optical emission spectrometer (ICP-OES), as described by Olajire and Ayodele (1997). The level of both organic and inorganic https://doi.org/10.5194/aab-69-251-2026

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers 253 Table 1. Ingredients and chemical composition of experimental diets. Ingredients (g kg−1 )

Starter phase (1–14 d of age) Grower phase (15–30 d of age) Finisher phase (31–42 d of age)

Yellow corn Soybean meal Corn gluten meal Limestone Dicalcium phosphate Vitamin and mineral premix1 NaCl DL-methionine L-lysine (HCL) Vegetable oils 550.0 324.0 55.0 11.0 17.5 3.0 3.0 3.1 3.4 30.0 617.9 260.0 54.0 11.2 15.0 3.0 3.0 3.0 2.9 30.0

682.0 212.0 40.0 11.0 13.0 3.0 3.0 2.0 3.5 30.5 Total 1000 1000 1000 868.0 12.69 221.0 6.9 10.6 13.4 79.0 9.1 4.6 52.1 47.0 52.5 0.626 874.0 13.03 193.4 6.0 9.4 11.8 80.0 8.5 4.1 61.3 43.3 55.3 0.673 869.0 13.28 178.0 5.1 8.2 10.6 77.0 7.9 3.6 71.9 47.5 57.4 0.704

Analysed2 and calculated3 values Dry matter2 , g kg−1 Metabolizable energy3 , MJ kg−1 Crude protein2 , g kg−1 Methionine3 , g kg−1 Sulfur amino acids (SAAs)3 , g kg−1 Lysine3 , g kg−1 SAA/lysine ratio, % Calcium3 , g kg−1 Available phosphorus3 , g kg−1 Crude fat2 , g kg−1 Crude fibre2 , g kg−1 Ash2 , g kg−1 Chromium2 , mg kg−1 diet

1 Per kilogram of diet: vitamin A, 24 mg; vitamin E, 20 mg; menadione, 2.3 mg; vitamin D3, 0.05 mg; riboflavin, 5.5 mg;

calcium pantothenate, 12 mg; nicotinic acid, 50 mg; choline chloride, 600 mg; vitamin B12, 10 µg; vitamin B6, 3 mg; thiamine, 3 mg; folic acid, 1 mg; d-biotin, 0.05 mg; Mn, 80 mg kg−1 ; Zn, 60 mg kg−1 ; Fe, 35 mg kg−1 ; Cu, 8 mg kg−1 ; Se, 0.60 mg kg−1 . 2 Analysed values: dry matter, crude protein, crude fat (ether extract), crude fibre, and ash were determined according to AOAC (1995). Chromium content of the diets was determined by ICP-OES (Varian 720-ES) as described by Olajire and Ayodele (1997); chromium distribution homogeneity was verified by ICP-OES analysis of the final diets. 3 Calculated values: metabolizable energy, amino acids (methionine, sulfur amino acids, and lysine), calcium, and available phosphorus were calculated based on ingredient composition and NRC (1994) nutrient tables/recommendations.

chromium was chosen based on a review of the scientific literature and the indications of the producers. Previous studies indicate not only that organic chromium, such as picolinate, tends to have a higher absorbability under standard conditions, but also that inorganic chromium chloride can positively affect growth performance at optimal levels under stress conditions (Jain et al., 2018; Arif et al., 2019). The responses to chromium supplements may vary greatly depending on the environmental context and the specific needs of each organism under stress. The ingredients and chemical composition of the basal starter, grower, and finisher diets are presented in Table 1. Chromium was mixed directly into the chicken diet at the concentrations indicated. Chromium sources were first premixed using a blender with a small amount of the basal diet to obtain a homogeneous micro-premix, which was then incorporated into the complete mash diet using mechanical mixing. The homogeneity https://doi.org/10.5194/aab-69-251-2026

of chromium distribution was verified by ICP-OES analysis of the final diets. Although pelleting can further improve homogeneity, mash diets are commonly used in experimental trials to avoid heat-induced degradation of organic chromium forms. During 1–24 d of age, the birds were kept under the same temperature conditions (32, 30, and 28 °C during the first, second, and third week, respectively). The chickens were housed in a semi-open room. Then, during 25–42 d of age, birds were kept for 3 successive days (Monday, Tuesday, and Wednesday) weekly at 36 ± 2 °C and 75 %–85 % relative humidity from 10:00 to 17:00. All experimental groups, including the control group, were exposed to the same heat stress conditions; therefore, the control birds represent heatstressed broilers fed a basal diet without chromium supplementation. When not exposed to heat, the birds were kept under thermoneutral conditions (25 ± 2 °C). During the entire experimental period, the chicks were kept under similar Arch. Anim. Breed., 69, 251–263, 2026

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers

managerial and hygienic conditions. Chickens were provided with a 23:1 daily light:dark cycle during the experimental period. Chickens were fed corn–soybean meal mash diets during days 1–14 d (starter diet), 15–30 d (grower diet), and 31– 42 d (finisher diet) of age. The ingredient and chemical composition of the experimental diets are reported in Table 1. Feed and water were provided ad libitum. Vaccination against avian influenza (H5N2) was performed under the advice of veterinary authorization. Chicks were vaccinated against Newcastle disease virus (NDV) using a live attenuated vaccine, Hitchner B1 (commercial name: ND Hitchner B1, MSD Animal Health, Intervet, the Netherlands), on day 7 of age, and the LaSota strain (commercial name: ND LaSota, MSD Animal Health, Intervet, the Netherlands) on days 20 and 30. Birds were vaccinated against avian influenza (H5N2) using an inactivated vaccine (commercial name: avian influenza H5N2, Zoetis, USA) on day 9 and against infectious bursal disease (Gumboro) using a live vaccine (commercial name: IBD Intermediate Plus, Ceva Santé Animale, France) on days 14 and 24. Birds and rations were weighed on the first and last (42) days of the experimental period to calculate body weight gain (BWG), feed intake (FI), feed conversion ratio (FCR), and mortality rate (MR). The European Production Efficiency Index (EPEI) was calculated as described by Metwally et al. (2020). At 42 d of age, five male chicks per treatment were randomly selected from the seven replicates and housed individually for the digestibility assay using the total excreta collection method. Chicks were fasted for 24 h and then fed their corresponding experimental diets for 72 h, in which feed intake and excreta produced during the period were determined. The excreta were collected for each replicate, cleaned of feathers and feed, weighed, and dried in a forced-air oven at 70 °C for 36 h. Samples were then ground and placed in screw-top glass jars until analysis of dry matter, organic matter, nitrogen, ether extract, and crude fibre (AOAC, 1995). The apparent digestibility (AD; %) of the nutrients was calculated using the following formula: [(IN − NE) / IN] × 100, where IN is the ingested nutrient (g), and NE is the nutrients in the excreta (g). Only for nitrogen was fecal N used instead of NE. The procedure described by Jakobsen et al. (1960) was used to separate fecal nitrogen from urine nitrogen in the excreta samples. At 42 d of age, eight broilers of both sexes were randomly selected from each treatment to cover all replicates (seven replicates), with one replicate contributing two birds. Sex was recorded, and birds were weighed after overnight fasting, slaughtered, and feather-picked. The total inedible parts (head, legs, and inedible viscera) were set aside, and the carcass was weighed. The internal organs, including the liver, gizzard, heart, spleen, pancreas, bursa of Fabricius, abdominal fat, and intestine, were separated and individually weighed; their relative weights were expressed as a percentage of the live body weight. The intestine weight was recorded in grams and expressed as a percentage of live body weight at slaughter, and the length (cm) of the intesArch. Anim. Breed., 69, 251–263, 2026

tine was measured as indicators of gastrointestinal development and potential adaptive responses to heat stress and dietary chromium supplementation. Eight samples per treatment, composed of 50 % breast meat and 50 % thigh meat, were weighed and kept in an electric drying oven at 70 °C for 24 h until a constant weight was achieved. The dried flesh was finely ground using a suitable mixer to pass through a sieve (1 mm) and then carefully mixed. The air-dried samples were stored in airtight glass containers for subsequent analyses. The dry matter, nitrogen, fat, and ash contents were determined according to AOAC (1995). The physical characteristics of meat (breast and thigh meat) were determined using eight fresh-meat samples per treatment. Water-holding capacity (WHC) and tenderness were measured according to the method of Volvoinskaia and Kelman (1962), in which 0.3 g minced meat tissues were put under an ashless filter paper and pressed for 10 min using 1 kg weight. Two zones formed on the filter paper. Surface areas were measured using a planimeter. WHC was calculated by subtracting the internal zone from the outer zone. The internal zone is due to meat pressing, which indicates tenderness. The pH value was measured using 10.0 g of prepared samples of meat and drip blended with 50 mL of distilled water for 10 min, and then the pH value was measured (Aitken et al., 1962). The colour intensity of the meat and drip was determined by shaking 10 g with 50 mL distilled water in a dark room for 10 min. The samples were filtered, and the colour intensity (absorbency) was measured photometrically at 543 nm (Husani et al., 1950). Mortality during the experiment was negligible and did not significantly affect the final data. Animals were carefully monitored and kept in suitable conditions to minimize the impact of thermal stress on mortality.

Data were analysed using the GLM procedure (PROC GLM) of SAS software (SAS Institute Inc., Cary, NC, USA). The experiment was conducted as a completely randomized design with seven dietary treatments and seven replicates (cages) per treatment, with five birds per replicate. The dietary treatments consisted of an unsupplemented control diet and six chromium-supplemented diets arranged as two chromium sources (organic or inorganic) at three supplemental levels (100, 200, or 400 ppb). Because the control diet did not include a chromium source, the source × level interaction was evaluated only among chromium-supplemented treatments (100–400 ppb), whereas the 0 ppb unsupplemented control group was retained as an external reference for comparison. Planned contrasts were additionally used to compare the unsupplemented control with the chromiumsupplemented source × level combinations. Growth performance variables (body weight gain, feed intake, feed conversion ratio, and European Production Efficiency Index) were analysed using replicate (cage battery brooder or metal cage) https://doi.org/10.5194/aab-69-251-2026

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers 255

Table 2. LS means of productive performance of broilers at 42 d of age fed diets with different sources and concentrations of chromium supplementation (n = 7 replicates per treatment). Treatments BWG (g)

FI (g) FCR (kg kg−1 ) EPEI 1865a 1830b 0.03 3046 3030 0.490 1.64 1.67 0.068 250 252 0.791 3035 3036 3024 3054 0.182 1.87 a 1.64 b 1.69 b 1.63 b 0.039 174 258 238 257 0.128 Chromium source Organic Inorganic P value

Chromium concentrations (ppb) 1614c 1869a 1788b 1884a 0.001 0 100 200 400 P value Interaction (sources × concentrations of chromium) Control 0 1614c 3035 1.87a 173 Organic 100 200 400 1835b 1807b 1954a

3052 3029 3058 1.67bc 1.67bc 1.57d 265 242 244 Inorganic 100 200 400 1905a 1770b 1817b 3038 3021 3050 1.61cd 1.71b 1.68bc 251 235 270 SEM 20.1 27.2 0.026 15.3 P value 0.0001 0.089 0.01 0.148 a,b,c Means in a column under similar treatment conditions not sharing the same

superscript are significantly different (P <0.05). SEM – pooled standard error of the mean. BWG – body weight gain. FI – feed intake. FCR – feed conversion ratio. EPEI – European Production Efficiency Index. The control (0 ppb supplemented Cr) is shown for comparison; the source × level interaction refers to chromium-supplemented treatments only (100–400 ppb). The 0 ppb supplemented Cr control was compared with the chromium-supplemented treatments by planned contrasts within the GLM analysis.

as the experimental unit according to the following model: Y = µ + CRS + CRLV + (CRS × CRLV) + e, where Y is the observed value of the response variable for each replicate, µ is the overall mean, CRS is chromium source, CRLV is chromium level, and e is the residual error. For carcass traits, internal organs, and the chemical and physical traits of meat, individual bird measurements obtained at 42 d of age were analysed according to the following model: Y = µ + CRS + CRLV + Sex + (CRS × CRLV) + (CRS × Sex) + (CRLV × Sex) + (CRS × CRLV × Sex) + e, (1)

where Y is the observed value of the response variable for each individual bird, µ is the overall mean, Sex is the effect of sex, and e is the residual error. Because the experimental design was not fully factorial owing to the presence of the 0 ppb unsupplemented control group, least-squares means https://doi.org/10.5194/aab-69-251-2026

were used. Results are presented as least-squares means for chromium source, chromium level, and their interaction within chromium-supplemented treatments only (100– 400 ppb), whereas the 0 ppb control group is shown for comparison. Sex effects were retained in the model and are mentioned only when statistically significant; otherwise, results are presented averaged over sex, consistent with the layout of Tables 4–7. Normality and homogeneity of variances were assessed using the Shapiro–Wilk test (Shapiro and Wilk, 1965) and Levene’s test (Levene, 1960), respectively. Percentage data were log10-transformed when needed to improve normality. Mean differences were separated using the Student–Newman–Keuls test. Mortality rate was analysed using the chi-square test. Differences were considered significant at P < 0.05.

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers

Table 3. LS means of apparent digestibility (AD) of nutrients in broilers at 42 d of age fed diets with different sources and concentrations of chromium supplementation (n = 5 broilers (replicates) per treatment). Treatments

AD of nutrients, % DM OM CP EE CF Ash 76.7 76.7 0.28 83.7a 80.0b 0.03 86.1a 83.2 0.01 82.2 78.5 0.60 13.91 15.52 0.84 21.93 21.57 0.84 83.2b 83.4ab 84.2a 86.5a 0.01 77.3b 79.4ab 80.3a 81.3a 0.02 15.13 14.46 14.38 15.41 0.06

21.23 21.82 21.64 21.78 0.39 Chromium source Organic Inorganic P value Chromium concentration, ppb 0 100 200 400 P value 75.9 75.8 76.9 77.4 0.51 78.4b 80.4ab 82.2a 83.1a 0.01 Interaction (source × concentrations of chromium) Control

0 75.9 78.4 83.2 77.3 15.13 21.23 Organic 100 200 400 77.3 76.4 76.5 82.3 83.4 85.5 84.4 85.8 88.1 80.8 82.3 83.4 13.38 13.65 14.56 20.84 22.45 22.34 Inorganic 100 200 400 74.3 77.4 78.3 78.5 80.9 80.7

82.3 82.6 84.8 77.9 78.3 79.2 15.38 14.94 16.14 22.78 20.68 20.98 SEM 2.87 2.24 1.72 2.45 2.77 3.44 P value 0.38 0.42 0.68 0.43 0.91 0.57 a,b Means in a column under similar treatment conditions not sharing the same superscript are

significantly different at 5 %. SEM – pooled standard error of the mean. DM – dry matter, OM – organic matter, CP – crude protein, EE – ether extract, CF – crude fibre. The control (0 ppb supplemented Cr) is shown for comparison; the source × concentration interaction refers to chromium-supplemented treatments only (100–400 ppb).

3 Results Productive performance

There was no significant effect of Cr source on FI, FCR, and EPEI or of Cr levels on FI and EPEI. Within the chromium-supplemented treatments (organic vs. inorganic at 100–400 ppb), the source × level interaction affected BWG (P <0.0001) and FCR (P <0.01) (Table 2). Considering organic Cr, the BWG of birds receiving 400 ppb was higher than that of the groups receiving 100 and 200 ppb. Conversely, when birds were fed inorganic Cr, a better BWG was observed in the group receiving 100 ppb of Cr. Broilers fed diets containing Cr had a greater BWG than those in the control group. There was no difference between the BWG of birds receiving 400 ppb of organic Cr and those receiving diets with 100 ppb of inorganic Cr. The best FCR values were obtained with dietary supplementation with 400 ppb of organic Cr and 100 ppb of inorganic Cr. As FI was not affected, FCR reflected the improvement in the BWG. Arch. Anim. Breed., 69, 251–263, 2026

Supplementation of diets with organic Cr resulted in higher apparent digestibility (AD) of organic matter (OM; P <0.03) and crude protein (CP; P <0.01), whereas Cr levels affected (P <0.01) the AD of OM, CP, and EE (Table 3), with the best values obtained with 200 and 400 ppb of Cr. Neither carcass characteristics nor body organs were influenced (P >0.05) by the source × level interaction when averaged over sex; however, broilers fed diets containing organic Cr had a lower heart percentage (P <0.005) (Tables 4 and 5). Sex and its interactions with chromium source and level were tested for slaughter traits, but no significant effects were detected; therefore, results are presented averaged over sex. The treatments did not affect (P >0.05) the chemical composition, physical characteristics, or meat quality of broilers (Tables 6 and 7). 4

The calculated Cr content of the experimental diets ranged from 0.626 to 0.704 mg kg−1 diet. Although the basal diets https://doi.org/10.5194/aab-69-251-2026

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers 257

Table 4. LS means of percentage of carcass and abdominal fat of broilers at 42 d of age fed diets with different sources and concentrations of chromium supplementation (n = 8 broilers (replicates) per treatment. Treatments

Percentage of carcass and abdominal fat, % Dressing Front part Hind part Abdominal fat 68.9 69.2 0.820 34.6 33.9 0.343 29.3 30.5 0.081 0.808 0.670 0.324 35.2 35.0 34.3 33.4 0.255 30.4 29.8 30.5 29.4 0.386

0.50 0.67 0.82 0.73 0.675 Chromium source Organic Inorganic P value Chromium concentrations, ppb 0 100 200 400 P value 69.7 68.8 69.4 68.9 0.902 Interaction (sources × concentrations of chromium) Control

0 69.7 35.2 30.4 0.501 Organic 100 200 400 70.2 69.3 67.2 36.0 34.4 33.4 29.4 30.3 28.4 0.669 1.079 0.677 Inorganic 100 200 400 67.3 69.3 70.6 34.0 34.2 33.4 30.2 30.7 30.5 0.663 0.556 0.792 SEM 1.540

0.970 0.764 0.170 P value 0.139 0.543 0.514 0.147

SEM – pooled standard error of the mean. Values are least-squares means averaged over sex; sex and its interactions were included in the statistical model but are not shown because they were not statistically significant (P > 0.05). The control (0 ppb supplemented Cr) is shown for comparison; the source × concentration interaction refers to chromium-supplemented treatments only (100–400 ppb).

contained measurable background chromium, native Cr in conventional feed ingredients is generally characterized by low availability, which may help explain the response observed even at the lowest supplemental level. The Cr content in corn, soybean meal, and corn gluten meal was 0.055, 0.124, and 0.9 ppm, respectively. The observed Cr content in the feed ingredients used in our study, specifically 0.055 ppm in corn and 0.124 ppm in soybean meals, is indeed lower than the values reported by Bohlmann (2012), who identified Cr concentrations of 0.9 ppm in corn and 0.2 ppm in soybean meal. This discrepancy could be attributed to variations in agricultural practices, soil composition, and environmental factors that influence the mineral content of crops. Moreover, the differences in the Cr content could also result from methodological variations in measuring Cr concentrations or the specific batches of ingredients used in the study. There are no established Cr requirements for poultry, emphasizing the importance of studying the impact of different Cr sources and levels on broiler performance. Cr has been studied as an anti-heat-stress agent for broilers (Dalólio et al., 2021; Kim

et al., 2021; Piray and Foroutanifar, 2021; Kim et al., 2023). The markedly lower body weight gain and poorer feed conversion ratio observed in the control group confirm the effectiveness of the heat stress model applied in this study and are consistent with the well-documented negative effects of cyclic heat stress on broiler performance. Because no thermoneutral group was included, the control group was intentionally designed to serve as a heat-stressed reference, allowing the effects of chromium supplementation to be evaluated specifically under thermal stress conditions. Although birds were exposed to high ambient temperatures for 3 consecutive days per week rather than continuously, the repeated cyclic exposure (36 ± 2 °C for 7 h d−1 from 25 to 42 d of age) can be classified as chronic cyclic heat stress. This experimental model is widely used in poultry research to simulate field conditions in which broilers are subjected to recurrent heat load over extended periods. The absence of a thermoneutral control group represents a limitation of the present study, as it does not allow a direct comparison between thermoneutral and heat-stressed conditions. However, the experimental de- Arch. Anim. Breed., 69, 251–263, 2026

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers

Table 5. LS means of internal organs in broilers at 42 d of age fed diets containing different supplementations chromium sources and concentrations (n = 8 broilers (replicates) per treatment). Treatments

Internal organs, % Heart Pancreas Gizzard Liver Proventriculus Intestine Weight, % Length, cm Chromium source 0.503b 0.582a 0.005 Organic Inorganic P value 0.223 0.214 0.482 1.73 1.73 0.994 2.31 2.14 0.090

0.381 0.386 0.829 3.76 3.96 0.195 151 162 0.003 0.249 0.217 0.229 0.209 0.467 1.71 1.69 1.82 1.69 0.186 2.48 2.37 2.21 2.11 0.129 0.430 0.376 0.399 0.376 0.609 4.63 3.97 3.80 3.81 0.602 157 157 155 158 0.765

Chromium concentrations, ppb 0 100 200 400 P value 0.528 0.533 0.545 0.549 0.865 Interaction (sources × concentrations of chromium) Control 0 0.528 0.249 1.71 2.48 0.430 4.63 157 Organic 100 200 400 0.497 0.475 0.536

0.228 0.241 0.201 1.71 1.78 1.70 2.56 2.29 2.10 0.371 0.396 0.378 3.83 3.89 3.57 154 149 151 Inorganic 100 200 400 0.568 0.615 0.563 0.207 0.217 0.218 1.66 1.86 1.67 2.17 2.14 2.11 0.381 0.404 0.373 4.10 3.71 4.05

160 162 166 SEM 0.033 0.016 0.082 0.126 0.027 0.181 4.312 P value 0.240 0.367 0.688 0.286 0.954 0.188 0.501

a,b Means in a column under similar treatment conditions not sharing the same superscript are significantly different at 5 %. SEM – pooled

standard error of the mean. Sex effect and sex × chromium treatment interactions were tested but are not shown. Values are least-squares means averaged over sex; sex and its interactions were included in the statistical model but are not shown because they were not statistically significant (P > 0.05). The control (0 ppb supplemented Cr) is shown for comparison; the source × concentration interaction refers to chromium-supplemented treatments only (100–400 ppb).

sign was specifically aimed at evaluating the relative effects of organic and inorganic chromium supplementation under heat stress conditions. Therefore, the control group consisted of heat-stressed birds fed a basal diet without chromium supplementation and served as an appropriate reference to assess chromium-mediated responses under identical environmental conditions. Heat stress triggers the release of corticosteroids, affecting glucose and mineral metabolism and immune function (Siegel, 1995). It also increases Cr mobilization from tissues and excretion through urine (Sahin et al., 2002), potentially leading to marginal Cr deficiency or an increased Cr requirement (Feng et al., 2021). Supplementing broiler diets with Cr can reduce glucocorticoid levels, as reported by Bahrami et al. (2012). Organic Cr is absorbed more efficiently (25 %–30 %) than inorganic Cr (1 %– 3 %) (Piva et al., 2003; Król et al., 2017). Moreover, the absorption rate is inversely proportional to the dietary Cr level (Kobla and Volpe, 2000; Vincent, 2000). Cr enhances insulin

sensitivity, potentially stimulating protein synthesis and inhibiting proteolysis (Tesseraud et al., 2007). These show the differences in Cr utilization among sources and levels and warrant further research. The highest BWG and FCR values were observed in birds fed diets with 400 ppb of organic Cr and 100 ppb of inorganic Cr, with BWG surpassing that of the control group. Although organic chromium is four times more concentrated than inorganic chromium, its absorption by the body is very low. However, organic chromium improves nutrient absorption and protein deposition more effectively than inorganic chromium, which explains why better body weight gains (BWGs) are achieved at a concentration of 400 ppb, despite the low absorption rate. Increasing inorganic Cr levels worsened BWG and FCR, likely due to decreased digestibility rates. Arif et al. (2019) found that dietary Cr propionate at 400 ppb improved BWG, while FI and FCR were better at 200 ppb. Including Cr propionate (0.1 to 0.3 mg kg−1 ) in broiler diets improved BWG and FCR

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers 259

Table 6. LS means of meat chemical composition of 42 d old broiler chickens fed diets with different supplementations chromium sources and concentrations, on a fresh-weight basis (n = 8 broilers (replicates) per treatment). Treatments

Chemical composition, % Dry matter Protein Lipids Ash 25.0 25.0 0.942 18.9 18.8 0.586 4.93 5.00 0.422 1.20 1.19 0.683 25.1 25.0 25.0 25.0 0.996 18.9 18.8 18.9 18.7 0.532 5.01 4.99 4.89 5.04 0.414 1.18 1.19 1.19 1.20 0.606

Chromium source Organic Inorganic P value Chromium concentrations, ppb 0 100 200 400 P value Interaction (sources × concentrations of chromium) Control 0 25.1 18.9 5.01 1.18 Organic 100 200 400 25.1 25.0 25.0

18.8 19.0 18.8 4.98 4.80 5.01 1.19 1.19 1.21 Inorganic 100 200 400 25.0 25.1 25.1 18.8 18.9 18.7 5.00 4.97 5.05 1.19 1.18 1.19 SEM 0.095 0.135 0.087 0.011 P value 0.939 0.951 0.774 0.880

SEM – pooled standard error of the mean. Values are least-squares means averaged over sex; for the traits reported in this table, sex and its interactions were included in the statistical model but are not shown because they were not statistically significant (P > 0.05). The control (0 ppb supplemented Cr) is shown for comparison; the source × concentration interaction refers to chromium-supplemented treatments only (100–400 ppb).

without affecting FI (Hayat et al., 2020). However, Ghazi et al. (2012) reported no effect of 0.6 and 1.2 mg kg−1 of Cr on broilers’ performance under heat stress. Dalólio et al. (2021) also found no effect of Cr methionine (0.1–1.2 mg kg−1 ) on broilers’ performance at 43 d of age. Wang et al. (2022) noted that 0.4 and 0.8 mg kg−1 Cr picolinate in heat-stressed broiler diets decreased BWG and FI and increased FCR. Organic Cr improved OM and CP digestibility more than inorganic Cr due to its higher absorption rate, affecting nutrient transporter expression. Cr supplementation alleviates the negative effect of heat stress on digestibility by increasing the expression of nutrient transporters in laying hens (Orhan et al., 2019). Diets with 200 and 400 ppb Cr resulted in better AD of OM, CP, and EE, enhancing nutrient digestibility. Hens fed diets with 1.6 ppm CrPic (12.43 % Cr) or 0.788 ppm CrHis (25.22 % Cr) per kg, providing 200 mg elemental Cr per tonne, showed better digestibility of dry matter, organic matter, and crude protein due to increased transporter expression for carbohydrates, fats, and amino acids in laying hens (Orhan et al., 2019). Wang et al. (2022) also found in- https://doi.org/10.5194/aab-69-251-2026

creased glucose transporter expression in the jejunum with 0.4 mg kg−1 Cr picolinate of heat-stressed broiler chickens. Broilers fed organic Cr had lower relative heart weights than those fed inorganic Cr. Heat stress reduces feed intake and circulating glucose (Pearce et al., 2013). Less absorbed inorganic Cr has a lower effect on insulin sensitivity, leading to less glucose uptake by myocardial cells. Energy metabolism shifts to fatty acid oxidation, forming advanced glycation end products that increase heart weight (Letonja and Petrovic, 2014). This study’s findings align with those of other studies observing non-significant improvements in broiler carcass characteristics and internal organs (Bahrami et al., 2012; Ghanbari et al., 2012; Arif et al., 2019). Anandhi et al. (2006) reported reduced abdominal fat thickness and muscle cholesterol in Cr-supplemented broiler chickens. Cr supplementation increased protein content in broiler meat (Anandhi et al., 2006; Saikat et al., 2008; Toghyani et al., 2008). Organic Cr increased carcass weight and yields of liver, heart, spleen, and gizzard, while reducing abdominal fat in broilers (Sahin et al., 2003; Saikat et al., 2008; Noori

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers

Table 7. LS means of physical characteristics of meat from broiler chickens at 42 d of age fed diets containing different supplementations chromium sources and concentrations (n = 8 broilers (replicates) per treatment).

Treatments pH Physical characteristics of meat Colour, absorbance Tenderness, at 543 nm cm2 /0.3 g of meat WHC, cm2 /0.3 g of meat Chromium source Organic Inorganic P value 6.66 6.65 0.711 0.196 0.190 0.386

2.84 2.84 0.966 4.90 4.85 0.410 0.206 0.196 0.192 0.191 0.812 2.84 2.83 2.85 2.84 0.948 4.85 4.88 4.85 4.85 0.881 Chromium concentrations, ppb 0 100 200 400 P value 6.73 6.69 6.67 6.63 0.381 Interaction (sources × concentrations of chromium) Control

0 6.73 0.206 2.84 4.85 Organic 100 200 400 6.69 6.68 6.63 0.199 0.196 0.192 2.83 2.83 2.86 4.91 4.91 4.89 Inorganic 100 200 400 6.64 6.70 6.63 0.193 0.187 0.191 2.83 2.87 2.83 4.80 4.87 4.88 SEM 0.044

0.008 0.070 0.079 P value 0.765 0.808 0.896 0.799

SEM – pooled standard error of the mean. WHC – water-holding capacity. Values are least-squares means averaged over sex; for the traits reported in this table, sex and its interactions were included in the statistical model but are not shown because they were not statistically significant (P > 0.05). The control (0 ppb supplemented Cr) is shown for comparison; the source × concentration interaction refers to chromium-supplemented treatments only (100–400 ppb).

et al., 2012). Dalólio et al. (2021) found a quadratic effect of Cr methionine (0.1–1.2 mg kg−1 ) on abdominal fat and the heart weight of broiler chickens, with optimal values at 0.75 and 0.43 mg kg−1 Cr, respectively. Hayat et al. (2020) also found increased heart weight with dietary Cr propionate (0.1–0.3 mg kg−1 ) in broiler chickens. Regarding meat quality, Souza et al. (2010) observed a quadratic effect of organic Cr (150–600 mg kg−1 ) on breast meat fat content in broilers, with a 7.03 % reduction at 218.2 mg kg−1 Cr. Untea et al. (2019) reported increased crude protein, Cr, Zn, and Fe levels in broiler meat with dietary Cr picolinate (0.2 and 0.4 mg kg−1 ). Other researchers have noted positive effects of Cr on meat quality of broilers (Huang et al., 2015). Potential environmental concerns related to chromium supplementation in animal nutrition should also be considered. Background chromium concentrations in agricultural soils typically range from 10–100 mg kg−1 , and regulatory limits for total chromium in soils are generally set well above these values, depending on national and international guidelines. In the present study, chromium inclusion levels (100–400 ppb

in feed) resulted in total dietary chromium concentrations far below levels commonly associated with environmental contamination. Furthermore, all chromium sources used were in the trivalent form (Cr3+ ), which is characterized by low mobility and limited bioavailability in soils compared with hexavalent chromium. Accordingly, when chromium is applied at nutritionally relevant levels and under controlled feeding conditions, the risk of environmental chromium accumulation through poultry manure is expected to be minimal. Nevertheless, long-term investigations evaluating chromium excretion and soil accumulation remain necessary to fully assess the environmental sustainability of chromium supplementation in poultry production systems. 5

In conclusion, supplementing broiler diets with 400 ppb of organic chromium (Cr) or 100 ppb of inorganic Cr from 1 to 42 d of age significantly enhances growth performance and nutrient digestibility under cyclic chromium inclusion levels https://doi.org/10.5194/aab-69-251-2026

Y. A. Attia et al.: Enhancement of productive performance, nutrient digestibility, and meat quality in broilers

underheat stress conditions. Specifically, organic Cr supplementation was found to improve feed digestibility more effectively compared to inorganic Cr at a higher concentration. These findings suggest that organic Cr is more beneficial in mitigating the negative effects of heat stress on broiler chickens. Furthermore, the study identifies optimal dosages for both organic (400 ppb) and inorganic (100 ppb) Cr that maximize production performance and nutrient utilization. This research provides valuable insights into the nutritional management of broiler chickens exposed to thermal stress, offering practical recommendations to enhance poultry health and efficiency. The results underscore the importance of selecting appropriate sources and dosages of Cr to improve the productivity and resilience of broiler chickens in challenging environmental conditions. However, concerns can be raised about the environmental impact of using chromium, both organic and inorganic, in chicken feed. Although the study highlights the benefits of Cr on performance and nutrient digestibility in chickens under heat stress, the accumulation of chromium in the environment could represent a potential risk, especially if the amounts used are not carefully managed. Future research could consider not only the long-term health effects on chickens, but also the environmental impact of using Cr in poultry production systems. Future studies should include thermoneutral control groups and long-term evaluations of chromium excretion and environmental accumulation to further strengthen conclusions regarding both physiological efficacy and environmental sustainability. In accordance with the primary objective of this research, the present results support the practical application of optimized chromium inclusion levels under cyclic heat stress conditions.

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# 开放获取档案:动物育种

## 不同浓度有机铬和无机铬对循环热应激条件下肉鸡生产性能、营养物质消化率和肉品质的改善

**Youssef Abdelwahab Attia¹, Nicola Francesco Addeo², Fulvia Bovera², Rashed Abdullah Alhotan³, Khalid Ali Asiry¹, Mohamed Alsaeed Al-Banoby⁴, El-Shahat Mohamed Qota⁵, Adel Daifallah Al-qurashi¹, Ahmed Shaban Awad⁶**

¹ 沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学环境科学学院农业系可持续农业研究组 ² 意大利那不勒斯费德里科二世大学兽医学与动物生产系可持续农业研究组 ³ 沙特阿拉伯利雅得沙特国王大学食品与农业科学系动物生产专业 ⁴ 沙特阿拉伯哈伊勒工业地区沙梅尔动物饲料厂 ⁵ 埃及吉萨多基农业研究中心动物生产研究所家禽营养系 ⁶ 埃及吉萨多基农业研究中心动物生产研究所兔、火鸡与水禽系

**通讯作者:** Youssewahab Attia (yaattia@kau.edu.sa), Nicola Francesco Addeo (nicolafrancesco.addeo@unina.it), Fulvia Bovera (bovera@unina.it), Rashed Abdullah Alhotan (ralhotan@ksu.edu.sa)

**收稿日期:** 2024年11月8日 – **修改日期:** 2026年1月8日 – **接受日期:** 2026年1月15日 – **发表日期:** 2026年4月28日

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**摘要:** 日粮中补充铬(Cr)可能是减轻热应激及其相关不良后果的有效手段。本研究旨在探究不同水平的有机铬和无机铬补充对循环热应激条件下肉仔鸡生产性能、营养物质消化率和肉品质的影响。试验共选用245只1日龄刚出壳的肉仔鸡,随机分为7个处理组,每个处理7个重复,每重复5只鸡。对照组饲喂不添加铬的基础日粮,其余6个处理组分别饲喂在基础日粮中添加100、200和400 ppb有机铬或无机铬的日粮。从25日龄至42日龄,每周连续3天对家禽施加热应激。在铬补充处理组中,铬源与铬水平的交互作用显著影响体增重(BWG)和料重比(FCR)(P < 0.01),其中以400 ppb有机铬组和100 ppb无机铬组获得最佳值。日粮补充有机铬显著提高了有机物(OM;P < 0.05)和粗蛋白(CP;P < 0.01)的表观消化率(AD),而铬水平显著影响OM、CP和粗脂肪(EE)的表观消化率(P < 0.01),其中以200和400 ppb铬组效果最佳。补充400 ppb有机铬或100 ppb无机铬可改善热应激条件下肉仔鸡的生长性能和营养物质消化率。这些发现与研究目标一致,并支持采用铬源特异性补充策略来缓解肉鸡的循环热应激。

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## 1 引言

高温环境对家禽存活率、生产性能和产品品质的不利影响已被广泛记载,给众多农业企业带来了持续的经济挑战。热应激家禽表现为采食量下降,同时体成分发生改变,特征为脂质沉积增加和肌肉蛋白质含量降低(Abdel-Moneim等,2021)。热胁迫诱导大量自由基产生,损害肉品质和动物健康,同时伴随酸中毒,降低肉的保水性,影响肉的质地(Nawaz等,2021),并扰乱营养转运蛋白的表达(Orhan等,2019)。通过维持现代家禽养殖场适宜的温湿度来进行有效管理可以缓解热应激(Saleh等,2023)。然而,此类方法成本高昂,增加了生产费用,且在许多发展中国家仍难以普及(Nawab等,2018)。铬(Cr)补充作为热应激缓解剂在畜禽养殖中日益受到重视(Shan等,2020;Wang等,2023;Dalólio等,2024;Apalowo等,2024)。Piray和Foroutanifar(2021)以及Kim等(2023)分别推荐以1 mg kg⁻¹或0.687 mg kg⁻¹的水平补充铬来减轻家禽热应激的不利影响,且不受铬源限制。铬在日粮中可以以无机或有机形式添加。市售有机铬主要有四种形式:丙酸铬、吡啶甲酸铬、蛋氨酸铬和酵母铬。吡啶甲酸铬于1996年获美国食品药品监督管理局(FDA)批准用于兽医领域,是最早被引入的有机铬形式(Chandrasekar和Balakrishnan,2019)。铬通过胰岛素信号通路在碳水化合物、蛋白质和脂质代谢中发挥关键作用,增强家禽骨骼肌中氨基酸和葡萄糖的吸收(Chandrasekar和Balakrishnan,2019)。此外,铬激活胰岛素受体并动员葡萄糖转运蛋白4型(GLUT 4)以改善葡萄糖摄取(Vincent,2015),从而可能提高营养利用效率和生产性能。然而,铬补充对肉仔鸡生产的影响仍存在争议。部分研究表明铬补充可能改善生产性能和胴体特性(Huang等,2016;Lu等,2019;Hayat等,2020;Dalólio等,2021;Youssef等,2022;Fraz等,2023),但其他研究未发现显著效果(Lee等,2003;Souza等,2010;Kim等,2021)。Orhan等(2019)研究表明,补充吡啶甲酸铬或组氨酸铬可改善蛋鸡的营养物质消化率,凸显了该微量元素通过增加营养转运蛋白表达在家禽营养中的重要性。

铬作为饲料添加剂的监管地位在不同地理区域存在差异。在欧盟,铬未被授权作为一般营养性添加剂;但特定铬化合物在经欧洲食品安全局(EFSA)科学评估并根据(EC)第1831/2003号法规获得正式授权后,可用于规定的动物物种和添加水平。在美国,丙酸铬获食品药品监督管理局(FDA)批准作为食用动物(包括家禽)的饲料添加剂,在特定使用条件和最高添加限量下使用。在沙特阿拉伯,含铬饲料添加剂的使用须经相关主管部门进行产品注册和审批,目前尚无铬作为饲料添加剂的公开通用授权。本研究旨在比较不同浓度有机铬和无机铬在缓解肉鸡热应激方面的效果,全面研究其对生长性能的影响。此外,本研究有助于确定有机铬和无机铬的最佳添加量,以最大化热应激条件下肉鸡的生产性能和营养物质消化率。最后,本研究为不同铬源的现有文献做出贡献,提供了关于特定营养物质消化率影响的详细见解,并完善了热应激家禽的营养管理策略。

## 2 材料与方法

### 2.1 试验动物与试验设计

试验选用245只1日龄Cobb500肉仔鸡(雌雄兼有),佩戴翅号,按相近初始体重采用完全随机设计分为7个处理组,每个处理7个重复,每重复5只鸡。样本量的选择基于管理操作的便利性,同时保持足够的重复数以获得统计功效并最小化偶然因素对结果的影响。选择7个处理组反映了研究者在高效检验铬存在与否的应答反应以及各铬源特定浓度效应方面的需求。设置未补充铬的对照组可与有机铬和无机铬处理组进行清晰比较,同时通过简单设计保持试验的处理功效。该方法使我们能够分离不同铬浓度的主要效应并验证研究假设。每个重复饲养在金属笼(35 cm × 25 cm × 30 cm,长×宽×高)中。阴性对照组饲喂不添加铬的基础日粮。其余6个处理组分别饲喂在基础日粮中添加100、200和400 ppb有机铬(吡啶甲酸铬,C₁₈H₁₂N₃O₆Cr;Nowfoods.com,加拿大制造,美国伊利诺伊州布卢明顿质检)或无机铬(三氯化铬,CrCl₃;Mubychem集团Muby Chemicals,印度西部)的日粮。日粮铬含量采用Varian 720-ES电感耦合等离子体发射光谱仪(ICP-OES)测定,方法参照Olajire和Ayodele(1997)的描述。有机铬和无机铬的添加水平基于科学文献综述和生产商的建议确定。前期研究表明,在标准条件下,吡啶甲酸铬等有机铬往往具有更高的吸收率,而在应激条件下,氯化铬等无机铬在最佳水平上也可对生长性能产生积极影响(Jain等,2018;Arif等,2019)。机体对铬补充剂的应答可能因环境背景和应激状态下各生物体的特定需求而存在显著差异。基础日粮(前期、生长期和育肥期)的原料组成和化学成分见表1。铬直接混入鸡日粮至指定浓度。铬源先与少量基础日粮用搅拌机预混以获得均匀的微预混料,再通过机械搅拌混入完全粉料日粮中。铬分布的均匀性通过ICP-OES分析最终日粮进行验证。虽然制粒可进一步改善均匀性,但粉料日粮常用于试验研究,以避免有机铬形式因热降解。

在1~24日龄期间,家禽保持在相同温度条件下(第一、二、三周分别为32°C、30°C和28°C)。鸡群饲养在半开放式舍内。随后在25~42日龄期间,每周连续3天(周一、周二和周三)在10:00至17:00将家禽置于36 ± 2°C、75%~85%相对湿度的环境中。所有试验组(包括对照组)均暴露于相同的热应激条件下,因此对照鸡代表饲喂未补充铬基础日粮的热应激肉鸡。在非热应激期间,家禽保持在热中性条件下(25 ± 2°C)。整个试验期间,雏鸡在相似的管理和卫生条件下饲养。试验期间每日光照:黑暗周期为23:1。雏鸡在1~14日龄(前期日粮)、15~30日龄(生长期日粮)和31~42日龄(育肥期日粮)饲喂玉米-豆粕粉料日粮。试验日粮的原料组成和化学成分见表1。饲料和饮水自由采食。禽流感(H5N2)疫苗接种在兽医指导下进行。雏鸡于7日龄用Hitchner B1株弱毒活疫苗(商品名:ND Hitchner B1,MSD动物健康,Intervet,荷兰)接种新城疫病毒(NDV),并于20和30日用LaSota株(商品名:ND LaSota,MSD动物健康,Intervet,荷兰)加强免疫。雏鸡于9日龄用灭活疫苗(商品名:禽流感H5N2,Zoetis,美国)接种禽流感(H5N2),并于14和24日龄用活疫苗(商品名:IBD Intermediate Plus,Ceva Santé Animale,法国)接种传染性法氏囊病(Gumboro)。在试验开始和结束(第42天)时称量鸡群和饲料重量,以计算体增重(BWG)、采食量(FI)、料重比(FCR)和死亡率(MR)。欧洲生产效率指数(EPEI)按Metwally等(2020)所述方法计算。

在42日龄时,每个处理从7个重复中随机选取5只公鸡,单独饲养,采用全收粪法进行消化率测定。雏鸡禁食24 h后饲喂相应试验日粮72 h,期间测定采食量和排出的排泄物量。收集每个重复的排泄物,去除羽毛和饲料残渣,称重,在70°C强制通风烘箱中干燥36 h。样品随后研磨,装入螺旋盖玻璃瓶中,用于分析干物质、有机物、氮、粗脂肪和粗纤维(AOAC,1995)。营养物质表观消化率(AD;%)按以下公式计算:[(摄入营养素 - 排泄物中营养素)/ 摄入营养素] × 100。对于氮,使用粪氮代替排泄物中营养素。排泄物样品中粪氮与尿氮的分离采用Jakobsen等(1960)所述方法。

在42日龄时,每个处理随机选取8只肉鸡(雌雄兼有),覆盖所有7个重复(其中一个重复贡献2只鸡)。记录性别,禁食过夜后称重、屠宰、去羽。将不可食部分(头、腿和不可食内脏)分离,称量胴体重。分离内脏器官(包括肝脏、肌胃、心脏、脾脏、胰腺、法氏囊、腹脂和肠道)并分别称重,其相对重量以活体重的百分比表示。肠道重量以克为单位记录,以屠宰时活体重的百分比表示,并测量肠道长度(cm),作为胃肠道发育和对应激及日粮铬补充潜在适应性反应的指标。

每个处理取8个样品(由50%胸肉和50%腿肉组成),称重后在70°C电热干燥箱中干燥24 h至恒重。干燥肉样用合适搅拌机研磨,过1 mm筛,仔细混合。风干样品密封于玻璃瓶中保存,用于后续分析。干物质、氮、脂肪和灰分含量按AOAC(1995)方法测定。

采用每个处理8个鲜肉样品测定肉(胸肉和腿肉)的物理特性。保水性(WHC)和嫩度按Volvoinskaia和Kelman(1962)方法测定:将0.3 g绞碎肉样置于无灰滤纸上,用1 kg重物加压10 min。滤纸上形成两个区域,用面积仪测量表面积。WHC由外圈面积减去内圈面积计算得出。内圈面积由肉样受压产生,反映嫩度。pH值测定:取10.0 g制备的肉样和渗出液,加入50 mL蒸馏水搅拌10 min,然后测定pH值(Aitken等,1962)。肉和渗出液的颜色强度测定:在暗室中将10 g样品与50 mL蒸馏水振荡10 min,过滤后在543 nm处用光度法测定颜色强度(吸光度)(Husani等,1950)。试验期间死亡率极低,未对最终数据产生显著影响。对动物进行仔细监测,并保持在合适条件下,以最小化热应激对死亡率的影响。

### 2.2 统计分析

数据采用SAS软件(SAS Institute Inc.,Cary,NC,USA)的GLM程序(PROC GLM)进行分析。试验采用完全随机设计,7个日粮处理,每个处理7个重复(笼),每重复5只鸡。日粮处理包括未补充对照日粮和6个铬补充日粮,按2个铬源(有机或无机)× 3个补充水平(100、200或400 ppb)排列。由于对照日粮未包含铬源,源×水平交互作用仅在铬补充处理(100~400 ppb)间评估,而0 ppb未补充对照组保留作为外部参照进行比较。此外使用计划对比将未补充对照与铬补充的源×水平组合进行比较。生长性能指标(体增重、采食量、料重比和欧洲生产效率指数)以重复(笼式育雏器或金属笼)为试验单位,按以下模型分析:

Y = μ + CRS + CRLV + (CRS × CRLV) + e

其中Y为每个重复响应变量的观测值,μ为总体均值,CRS为铬源,CRLV为铬水平,e为残差误差。

对于胴体性状、内脏器官以及肉的化学和物理性状,42日龄时获得的个体鸡只测量值按以下模型分析:

Y = μ + CRS + CRLV + Sex + (CRS × CRLV) + (CRS × Sex) + (CRLV × Sex) + (CRS × CRLV × Sex) + e

其中Y为每个个体响应变量的观测值,Sex为性别效应,e为残差误差。由于试验设计因存在0 ppb未补充对照组而非完全因子设计,采用最小二乘均值。结果以铬补充处理(100~400 ppb)的铬源、铬水平及其交互作用的最小二乘均值呈现,0 ppb对照组仅作比较。性别效应保留在模型中,仅在具有统计学显著性时提及;否则结果以性别间平均值呈现,与表4~7的布局一致。正态性和方差齐性分别采用Shapiro-Wilk检验(Shapiro和Wilk,1965)和Levene检验(Levene,1960)评估。百分比数据在需要时进行log₁₀转换以改善正态性。均值差异采用Student-Newman-Keuls检验进行分离。死亡率采用卡方检验分析。P < 0.05时认为差异显著。

## 3 结果

### 3.1 生产性能

铬源对FI、FCR和EPEI无显著影响,铬水平对FI和EPEI无显著影响。在铬补充处理组中(有机铬vs.无机铬,100~400 ppb),源×水平交互作用影响BWG(P < 0.0001)和FCR(P < 0.01)(表2)。

就有机铬而言,400 ppb组家禽的BWG高于100和200 ppb组。相反,当家禽饲喂无机铬时,100 ppb铬组观察到更好的BWG。饲喂含铬日粮的肉仔鸡BWG高于对照组。400 ppb有机铬组与100 ppb无机铬组家禽的BWG无差异。最佳FCR值出现在日粮补充400 ppb有机铬和100 ppb无机铬时。由于FI未受影响,FCR反映了BWG的改善。

日粮补充有机铬使有机物(OM;P < 0.03)和粗蛋白(CP;P < 0.01)的表观消化率(AD)更高,而铬水平影响(P < 0.01)OM、CP和EE的表观消化率(表3),其中以200和400 ppb铬获得最佳值。

胴体性状和内脏器官不受源×水平交互作用影响(P > 0.05,性别间平均值),但饲喂有机铬日粮的肉仔鸡心脏百分比更低(P < 0.005)(表4和5)。性别及其与铬源和水平的交互作用在屠宰性状上进行了检验,但未检测到显著效应,因此结果以性别间平均值呈现。

处理对肉仔鸡的化学成分、物理特性或肉品质无影响(P > 0.05)(表6和7)。

## 4 讨论

试验日粮的铬含量范围为0.626至0.704 mg kg⁻¹日粮。尽管基础日粮含有可测量的本底铬,但常规饲料原料中天然铬的利用率通常较低,这可能有助于解释即使在最低补充水平下也观察到的应答反应。玉米、豆粕和玉米蛋白粉中的铬含量分别为0.055、0.124和0.9 ppm。本研究中使用的饲料原料中观察到的铬含量,特别是玉米0.055 ppm和豆粕0.124 ppm,确实低于Bohlmann(2012)报道的值,后者鉴定玉米和豆粕中铬浓度分别为0.9 ppm和0.2 ppm。这种差异可归因于影响作物矿物质含量的农业实践、土壤组成和环境因素的变化。此外,铬含量的差异也可能源于铬浓度测量方法的差异或研究中使用的特定批次原料。家禽尚无确定的铬需要量,这凸显了研究不同铬源和水平对肉鸡性能影响的重要性。铬作为肉鸡抗热应激剂已被广泛研究(Dalólio等,2021;Kim等,2021;Piray和Foroutanifar,2021;Kim等,2023)。

对照组中观察到的体增重显著降低和料重比显著升高证实了本研究所施加热应激模型的有效性,且与循环热应激对肉鸡性能的充分记载的负面影响一致。由于未设置热中性对照组,对照组被有意设计为热应激参照,使铬补充的效果能够在热应激条件下进行专门评估。尽管家禽每周连续3天而非持续暴露于高温环境,但反复的循环暴露(25至42日龄期间每天7 h,36 ± 2°C)可被归类为慢性循环热应激。该试验模型在家禽研究中被广泛应用,以模拟肉鸡在较长时间内反复承受热负荷的田间条件。缺乏热中性对照组是本研究的局限性,因为它不允许在热中性和热应激条件之间进行直接比较。然而,试验设计专门旨在评估热应激条件下有机铬和无机铬补充的相对效果。因此,对照组由饲喂未补充铬基础日粮的热应激家禽组成,作为在相同环境条件下评估铬介导应答的适当参照。

热应激触发糖皮质激素释放,影响葡萄糖和矿物质代谢及免疫功能(Siegel,1995)。热应激还增加铬从组织中的动员和通过尿液排泄(Sahin等,2002),可能导致铬的边际缺乏或铬需要量增加(Feng等,2021)。向肉鸡日粮中补充铬可降低糖皮质激素水平,如Bahrami等(2012)所报道。有机铬的吸收效率(25%~30%)高于无机铬(1%~3%)(Piva等,2003;Król等,2017)。此外,吸收率与日粮铬水平成反比(Kobla和Volpe,2000;Vincent,2000)。铬通过增强胰岛素……

敏感性,可能刺激蛋白质合成并抑制蛋白质水解(Tesseraud等,2007)。这些结果表明不同来源和水平的铬(Cr)利用存在差异,值得进一步研究。在饲喂含400 ppb有机铬和100 ppb无机铬日粮的鸟类中,观察到最高的增重(BWG)和饲料转化率(FCR)值,其中BWG超过了对照组。尽管有机铬的浓度是无机铬的四倍,但其机体吸收率非常低。然而,有机铬比无机铬更有效地改善营养吸收和蛋白质沉积,这解释了为何在400 ppb浓度下尽管吸收率较低,仍能实现更好的体增重(BWG)。提高无机铬水平会恶化BWG和FCR,可能是由于消化率下降所致。Arif等(2019)发现,日粮中添加400 ppb的丙酸铬可改善BWG,而采食量(FI)和FCR在200 ppb时表现更佳。在肉鸡日粮中添加丙酸铬(0.1至0.3 mg kg⁻¹)可改善BWG和FCR。

Y. A. Attia等:肉鸡生产性能、养分消化率和肉品质的改善 259

表6. 饲喂不同铬源和浓度补充日粮的42日龄肉鸡鸡肉化学组成的LS均值(鲜重基础)(每个处理8只肉鸡(重复))。

处理

化学组成,% 干物质 蛋白质 脂质 灰分 25.0 25.0 0.942 18.9 18.8 0.586 4.93 5.00 0.422 1.20 1.19 0.683 25.1 25.0 25.0 25.0 0.996 18.9 18.8 18.9 18.7 0.532 5.01 4.99 4.89 5.04 0.414 1.18 1.19 1.19 1.20 0.606

铬源 有机 无机 P值 铬浓度,ppb 0 100 200 400 P值 互作(铬源×浓度) 对照 0 25.1 18.9 5.01 1.18 有机 100 200 400 25.1 25.0 25.0

18.8 19.0 18.8 4.98 4.80 5.01 1.19 1.19 1.21 无机 100 200 400 25.0 25.1 25.1 18.8 18.9 18.7 5.00 4.97 5.05 1.19 1.18 1.19 SEM 0.095 0.135 0.087 0.011 P值 0.939 0.951 0.774 0.880

SEM – 合并标准误。数值为按性别平均的最小二乘均值;对于本表中报告的性状,性别及其互作已纳入统计模型,但由于无统计学意义(P > 0.05)而未显示。对照(0 ppb补充Cr)仅供参考;源×浓度互作仅指铬补充处理(100–400 ppb)。

且不影响FI(Hayat等,2020)。然而,Ghazi等(2012)报道,在热应激条件下,0.6和1.2 mg kg⁻¹的Cr对肉鸡性能无影响。Dalólio等(2021)也发现蛋氨酸铬(0.1–1.2 mg kg⁻¹)对43日龄肉鸡性能无影响。Wang等(2022)指出,在热应激肉鸡日粮中添加0.4和0.8 mg kg⁻¹的吡啶甲酸铬会降低BWG和FI,并提高FCR。有机铬由于吸收率高于无机铬,因此比有机铬更改善有机物(OM)和粗蛋白(CP)的消化率,从而影响养分转运蛋白的表达。Cr补充通过增加蛋鸡中养分转运蛋白的表达来缓解热应激对消化率的负面影响(Orhan等,2019)。含200和400 ppb Cr的日粮使OM、CP和乙醚提取物(EE)的表观消化率(AD)更好,从而增强了养分消化率。饲喂每千克含1.6 ppm CrPic(12.43% Cr)或0.788 ppm CrHis(25.22% Cr)日粮的母鸡,每吨提供200 mg元素Cr,由于母鸡中碳水化合物、脂肪和氨基酸转运蛋白表达增加,其干物质、有机物和粗蛋白的消化率更好(Orhan等,2019)。Wang等(2022)还发现,在热应激肉鸡中,添加0.4 mg kg⁻¹吡啶甲酸铬可增加空肠中葡萄糖转运蛋白的表达。饲喂有机铬的肉鸡心脏相对重量低于饲喂无机铬的肉鸡。热应激会降低采食量和循环葡萄糖(Pearce等,2013)。吸收较少的无机铬对胰岛素敏感性影响较小,导致心肌细胞对葡萄糖的摄取减少。能量代谢转向脂肪酸氧化,形成晚期糖基化终产物,从而增加心脏重量(Letonja和Petrovic,2014)。本研究的结果与其他研究结果一致,这些研究观察到肉鸡胴体特性和内脏器官的改善不显著(Bahrami等,2012;Ghanbari等,2012;Arif等,2019)。Anandhi等(2006)报道,补充Cr的肉鸡腹部脂肪厚度和肌肉胆固醇降低。Cr补充增加了肉鸡肌肉中的蛋白质含量(Anandhi等,2006;Saikat等,2008;Toghyani等,2008)。有机铬增加了胴体重量以及肝脏、心脏、脾脏和肌胃的产量,同时减少了肉鸡的腹部脂肪(Sahin等,2003;Saikat等,2008;Noori等,2012)。Dalólio等(2021)发现蛋氨酸铬(0.1–1.2 mg kg⁻¹)对肉鸡腹部脂肪和心脏重量有二次效应,最佳值分别为0.75和0.43 mg kg⁻¹ Cr。Hayat等(2020)也发现,在肉鸡日粮中添加丙酸铬(0.1–0.3 mg kg⁻¹)会增加心脏重量。关于肉品质,Souza等(2010)观察到有机铬(150–600 mg kg⁻¹)对肉鸡胸肌脂肪含量有二次效应,在218.2 mg kg⁻¹ Cr时降低7.03%。Untea等(2019)报道,日粮中添加吡啶甲酸铬(0.2和0.4 mg kg⁻¹)可提高肉鸡肌肉中粗蛋白、Cr、Zn和Fe水平。其他研究者也注意到Cr对肉鸡肉品质的积极影响(Huang等,2015)。还应考虑与动物营养中铬补充相关的潜在环境问题。农业土壤中铬的背景浓度通常为10–100 mg kg⁻¹,土壤中总铬的监管限值通常设定得远高于此值,具体取决于国家和国际指南。在本研究中,铬添加水平(饲料中100–400 ppb)导致总膳食铬浓度远低于通常与环境污染相关的水平。此外,所有使用的铬源均为三价形式(Cr³⁺),与六价铬相比,其在土壤中具有低移动性和有限的生物利用度。因此,当以营养相关水平并在受控饲喂条件下施用铬时,通过家禽粪便造成环境铬积累的风险预计很小。然而,仍需进行长期研究,评估铬的排泄和土壤积累,以充分评估铬补充在家禽生产系统中的环境可持续性。

5

总之,在1至42日龄肉鸡日粮中补充400 ppb有机铬或100 ppb无机铬,可显著增强周期性热应激条件下的生长性能和养分消化率。具体而言,发现有机铬补充比更高浓度的无机铬更有效地改善饲料消化率。这些结果表明,有机铬在缓解热应激对肉鸡的负面影响方面更为有益。此外,本研究确定了有机铬(400 ppb)和无机铬(100 ppb)的最佳剂量,以最大化生产性能和养分利用。本研究为暴露于热应激的肉鸡的营养管理提供了有价值的见解,并提供了改善家禽健康和效率的实际建议。结果强调了在挑战性环境条件下选择合适的铬源和剂量以提高肉鸡生产力和抗逆性的重要性。然而,关于在鸡饲料中使用有机和无机铬对环境的影响,可能会提出一些担忧。尽管该研究强调了Cr对热应激下鸡性能和消化率的益处,但铬在环境中的积累可能构成潜在风险,特别是如果使用量未得到妥善管理。未来的研究不仅可以考虑对鸡的长期健康影响,还可以考虑Cr在家禽生产系统中使用对环境的影响。未来研究应包括热中性对照组以及铬排泄和环境积累的长期评估,以进一步加强关于生理功效和环境可持续性的结论。根据本研究的主要目的,目前的结果支持在周期性热应激条件下优化铬添加水平的实际应用。