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Effects of Formulation and Manufacturing Conditions on Protein Structure and Physical Stability制剂和制造条件对蛋白质结构和物理稳定性的影响
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Dry powder formulation suitable for administration via inhalation, for treating asthma, lung infections, cystic fibrosis comprises one or more antibodies or one or more angiogenesis inhibitors, a small molecular API, a stabilizer, and a dispersant适用于吸入给药的干粉制剂,用于治疗哮喘、肺部感染、囊性纤维化,包含一种或多种抗体或一种或多种血管生成抑制剂、一种小分子活性药物成分、一种稳定剂和一种分散剂
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Clustered regularly interspaced short palindromic repeat/CRISPR-associated protein 13a-based test strip useful for detecting infectious hypodermal and hematopoietic necrosis virus, comprises RPA system and CRISPR/Cas13a detection system基于成簇的规律间隔短回文重复序列/CRISPR相关蛋白13a的试纸条,可用于检测传染性皮下和造血坏死病毒,包括RPA系统和CRISPR/Cas13a检测系统
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Innovatív technológiák monoklonális antitestek előállítására és formulációjára用于生产和配制单克隆抗体的新型技术
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How spray drying processing and solution composition can affect the mAbs stability in reconstituted solutions for subcutaneous injections. Part II: Exploring each protein stabilizer effect喷雾干燥工艺和溶液组成如何影响皮下注射重构溶液中的单克隆抗体稳定性。第二部分:探索每种蛋白质稳定剂的作用
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Stability Comparison Between Microglassi fi cation and Lyophilization Using a Monoclonal Antibody使用单克隆抗体对微玻璃化和冻干的稳定性进行比较
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How spray drying processing and solution composition can affect the mAbs stability in reconstituted solutions for subcutaneous injections. Part I: Contribution of processing stresses against composition喷雾干燥工艺和溶液组成如何影响皮下注射重构溶液中的单克隆抗体稳定性。第一部分:工艺应力对组成的贡献
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Exploiting novel materials to overcome physiological barriers for oral inhalation of biologics利用新型材料克服生理屏障以实现生物制剂的口服吸入
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Stabilization of an infectious enveloped virus by spray-drying and lyophilization.通过喷雾干燥和冻干稳定传染性包膜病毒
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Liposome-based dry powder vaccine immunization targeting the lungs induces broad protection against pneumococcus靶向肺部的脂质体干粉疫苗接种诱导对肺炎球菌的广谱保护
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New anti-interleukin 4 receptor antibody or its antigen-binding fragment useful in pharmaceutical composition for preventing or treating inflammatory or autoimmune diseases e.g. rhinitis, conjunctivitis, periodontitis and otitis media新型抗白介素4受体抗体或其抗原结合片段在预防或治疗炎症或自身免疫性疾病(如鼻炎、结膜炎、牙周炎和中耳炎)的药物组合物中的应用
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How spray drying processing and solution composition can affect the mAbs stability in reconstituted solutions for subcutaneous injections. Part I: Contribution of processing stresses against composition.喷雾干燥工艺和溶液组成如何影响重组皮下注射溶液中单克隆抗体的稳定性。第一部分:工艺应力对组成的贡献。
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How spray drying processing and solution composition can affect the mAbs stability in reconstituted solutions for subcutaneous injections. Part II: Exploring each protein stabilizer effect.喷雾干燥工艺和溶液组成如何影响重组皮下注射溶液中单克隆抗体的稳定性。第二部分:探讨每种蛋白质稳定剂的作用。
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Preclinical validation of oral therapeutic lead proteins targeting epithelial GM1 ganglioside for ulcerative colitis therapy靶向上皮GM1神经节苷脂的口服治疗先导蛋白在溃疡性结肠炎治疗中的临床前验证
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Preventing norovirus and Clostridium difficile gastroenteritis by engineered probiotic yeast Saccharomyces boulardii secreting multi-specific single-domain antibodies通过工程益生菌酵母布拉迪酵母分泌多特异性单域抗体预防诺如病毒和艰难梭菌性肠胃炎
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Preventing norovirus and Clostridium difficile gastroenteritis by engineered probiotic yeast Saccharomyces boulardii secreting multi-specific single-domain antibodies通过工程益生菌酵母布拉迪酵母分泌多特异性单域抗体预防诺如病毒和艰难梭菌性肠胃炎
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Enhanced powder dispersion of dual-excipient spray-dried powder formulations of a monoclonal antibody and its fragment for local treatment of severe asthma单克隆抗体及其片段的双赋形剂喷雾干燥粉末制剂的粉末分散性增强,用于严重哮喘的局部治疗
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Progress towards elimination of onchocerciasis transmission in Mali: A 'pre-stop MDA' survey in 18 transmission zones.马里盘尾丝虫病传播消除进展:18个传播区的“暂停大规模药物干预前”调查
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Liposome-based dry powder vaccine immunization targeting the lungs induces broad protection against pneumococcus.靶向肺部的脂质体干粉疫苗接种诱导对肺炎球菌的广谱保护
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Impact of Processing Methods on the Physico-chemical Properties of Posaconazole Amorphous Solid Dispersions加工方法对泊沙康唑无定形固体分散体理化性质的影响