Engineering High-Performance Inhalable Monoclonal Antibody Powders via Spray Freeze Drying.

⚡ 摘要
期刊 European Journal Of Pharmaceutics And Biopharmaceutics : Official Journal Of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.v 类型 原创研究 (Original Research)

📄 英文摘要 English Abstract

EN

Spray freeze-drying (SFD) is a cutting-edge technique for producing dry powders, ideal for pulmonary drug delivery, owing to its ability to generate porous microparticles with low density and excellent aerodynamic properties. The SFD ... Preservation solution used for preparing a product for detecting the adiponectin content in human serum, plasma, or whole blood, comprises trisaminomethane, trehalose, Tween 20, sodium caseinate, polyvinylpyrrolidone, ProClin, Triton X, surfactant S13, and glyci

📄 中文摘要 Chinese Abstract

中文
喷雾冷冻干燥(SFD)是一种用于制备干粉末的前沿技术,因其能够生成低密度且空气动力学性能优异的多孔微粒,故非常适合肺部给药。一种用于制备检测人血清、血浆或全血中脂联素含量产品的保存液,包含三羟甲基氨基甲烷、海藻糖、吐温20、酪蛋白酸钠、聚乙烯吡咯烷酮、ProClin、曲拉通X、表面活性剂S13和甘氨酸。

📋 英文结构化总结 English Structured Summary

摘要整理

EN

Background:

Spray freeze-drying (SFD) is a cutting-edge technique for producing dry powders, ideal for pulmonary drug delivery, owing to its ability to generate porous microparticles with low density and excellent aerodynamic properties. A preservation solution used for preparing a product for detecting the adiponectin content in human serum, plasma, or whole blood, comprises trisaminomethane, trehalose, Tween 20, sodium caseinate, polyvinylpyrrolidone, ProClin, Triton X, surfactant S13, and glyci.

Methods:

Not provided in the provided text.

Results:

Not provided in the provided text.

Data Summary:

No quantitative results or key statistics are provided in the provided text.

Conclusions:

Not provided in the provided text.

Practical Significance:

The provided text indicates that SFD is ideal for pulmonary drug delivery and that the preservation solution is used for preparing a product for detecting the adiponectin content in human serum, plasma, or whole blood.

📋 中文结构化总结 Chinese Structured Summary

中文

背景:

喷雾冷冻干燥(SFD)是一种用于制备干粉末的前沿技术,因其能够生成低密度且空气动力学性能优异的多孔微粒,故非常适合肺部给药。一种用于制备检测人血清、血浆或全血中脂联素含量产品的保存液,包含三羟甲基氨基甲烷、海藻糖、吐温20、酪蛋白酸钠、聚乙烯吡咯烷酮、ProClin、曲拉通X、表面活性剂S13和甘氨酸。

方法:

所提供的文本中未提供。

结果:

所提供的文本中未提供。

数据摘要:

所提供的文本中未提供定量结果或关键统计数据。

结论:

所提供的文本中未提供。

实际意义:

所提供的文本表明,喷雾冷冻干燥(SFD)非常适合肺部给药,且该保存液用于制备检测人血清、血浆或全血中脂联素含量的产品。