Research Progress and Challenges of Anti-monkeypox Virus Drugs Targeting F13 Protein.

⚡ 摘要
期刊 Journal Of Medicinal Chemistry 类型 原创研究 (Original Research)

📄 英文摘要 English Abstract

EN

F13 protein is highly conserved in orthopoxviruses and serves as a classic broad-spectrum antiviral target. Nevertheless, clinical trials prove tecovirimat has weak efficacy and poor resistance profile. F13 inhibitors only hinder EEV ... Encapsulation of Protein-Based Drug Carriers for Controlled Loading and Releasing Efficiency: A Review Protein Journal Encapsulation of protein-based drug carriers represents a promising strategy for enhancing therapeutic efficiency by improving stability, bioav