Research progress on the role of protein tyrosine phosphatase receptor type R in cancer and its targeted drugs

⚡ 摘要
期刊 Chinese Bulletin Of Life Sciences 类型 原创研究 (Original Research)

📄 英文摘要 English Abstract

EN

Interaction between lncRNAs and RNA binding proteins, and their potential as drug targets in the therapy of liver cancer (Review). Biomedical Reports Liver cancer, including hepatocellular carcinoma (HCC) as the major type, is a serious malignant tumor with high morbidity and mortality worldwide. Long noncoding RNAs (lncRNAs) play an essential role in the pathogenesis and developme... A phase 1 study of HWK-007, a next-generation, protein tyrosine kinase 7 (PTK7)-targeted antibody-drug conjugate