Use of reagent for detecting plastin in preparing diagnostic reagent for auxiliary immune chemotherapy drug resistance of gastric cancer during local progressive phase, and detecting expression level of plastin protein, where progressive phase refers to e.g. drug resistance of gastric cancer cell

⚡ 摘要

检测Plastin的试剂在制备用于辅助诊断局部进展期胃癌免疫化疗耐药性的诊断试剂中的应用，以及检测Plastin蛋白表达水平，其中进展期指胃癌细胞耐药性等

期刊 Bispecific degrading antibody used in drug for treating Alzheimer's disease, progressive supranuclear palsy, frontotemporal dementia, and Parkinson's disease, comprises target protein-specific binding region, endocytic receptor-specific binding region, and a crystallizable fragment region 类型原创研究 (Original Research)

📄 英文摘要 English Abstract

Development and Mechanistic Evaluation of Cathepsin B-Activatable Peptide-Drug Conjugate PROTACs for Targeted Protein Degradation in Malignant Tumors: Advancing Precision Protein Degradation Therapeutics in Oncology Small Since the advent of proteolysis targeting chimeras (PROTACs), both small molecule PROTACs and peptide-based PROTACs have exhibited distinct advantages. However, PROTACs still exist issues such as poor membrane permeability, low bioava...

📄 中文摘要 Chinese Abstract

中文

自蛋白水解靶向嵌合体（PROTACs）问世以来，小分子PROTACs和肽基PROTACs均展现出各自的优势。然而，PROTACs仍存在膜通透性差、生物利用度低等问题。

📋 英文结构化总结 English Structured Summary

摘要整理

Background:

Since the advent of proteolysis targeting chimeras (PROTACs), both small molecule PROTACs and peptide-based PROTACs have exhibited distinct advantages. However, PROTACs still exist issues such as poor membrane permeability, low bioava...

Methods:

Not provided in the text.

Results:

Not provided in the text.

Data Summary:

Not provided in the text.

Conclusions:

Not provided in the text.

Practical Significance:

Not provided in the text.

📋 中文结构化总结 Chinese Structured Summary

中文

背景:

自蛋白水解靶向嵌合体（PROTACs）问世以来，小分子PROTACs和肽基PROTACs均展现出各自的优势。然而，PROTACs仍存在膜通透性差、生物利用度低等问题。

方法:

文中未提供。

结果:

文中未提供。

数据摘要:

文中未提供。

结论:

文中未提供。

实际意义:

文中未提供。