Research Progress on Exosome Application in Drug Delivery

⚡ 摘要

外泌体在药物递送中的应用研究进展

期刊 Advanced Applied Materials 发表日期 2019 ISSN 2003-0789 DOI 10.36822/adv.app.mater.201910 类型 原创研究 (Original Research)

📄 英文摘要 English Abstract

EN

cell-to-cell communication. The most studied extracellular vesicles are exosomes. Exosomes are discoid vesicles with diameters between 30 and 150 nm. They have good delivery abilities, and many studies have shown that as novel drug delivery systems exosome have low immunogenicity, high biocompatibility, and are a powerful and novel delivery platform for disease treatment. In this review, exosome drug-loading methods and the latest research results for their use in drug delivery are summarized to facilitate expansion of exosome applications in cancer treatment.

📄 中文摘要 Chinese Abstract

中文
细胞间通讯。研究最为广泛的外泌体是一类细胞外囊泡。外泌体是直径在30至150纳米之间的盘状囊泡。它们具有良好的递送能力,许多研究表明,作为新型药物递送系统,外泌体具有低免疫原性、高生物相容性,是疾病治疗中强大而新颖的递送平台。

📋 英文结构化总结 English Structured Summary

摘要整理

EN

Background:

cell-to-cell communication. The most studied extracellular vesicles are exosomes. Exosomes are discoid vesicles with diameters between 30 and 150 nm. They have good delivery abilities, and many studies have shown that as novel drug delivery systems exosome have low immunogenicity, high biocompatibility, and are a powerful and novel delivery platform for disease treatment.

Methods:

N/A - Review article

Results:

In this review, exosome drug-loading methods and the latest research results for their use in drug delivery are summarized to facilitate expansion of exosome applications in cancer treatment.

Data Summary:

Exosomes are discoid vesicles with diameters between 30 and 150 nm. They have low immunogenicity, high biocompatibility, and are a powerful and novel delivery platform.

Conclusions:

Exosomes have good delivery abilities, and as novel drug delivery systems they have low immunogenicity, high biocompatibility, and are a powerful and novel delivery platform for disease treatment.

Practical Significance:

Exosome applications in cancer treatment are facilitated through the summary of drug-loading methods and latest research results for their use in drug delivery.

📋 中文结构化总结 Chinese Structured Summary

中文

背景:

细胞间通讯。研究最为广泛的外泌体是一类细胞外囊泡。外泌体是直径在30至150纳米之间的盘状囊泡。它们具有良好的递送能力,许多研究表明,作为新型药物递送系统,外泌体具有低免疫原性、高生物相容性,是疾病治疗中强大而新颖的递送平台。

方法:

不适用——综述文章

结果:

本综述总结了外泌体的载药方法及其在药物递送中的最新研究成果,以促进外泌体在癌症治疗中的应用拓展。

数据概要:

外泌体是直径在30至150纳米之间的盘状囊泡。它们具有低免疫原性、高生物相容性,是一种强大而新颖的递送平台。

结论:

外泌体具有良好的递送能力,作为新型药物递送系统,它们具有低免疫原性、高生物相容性,是疾病治疗中强大而新颖的递送平台。

实践意义:

通过总结外泌体的载药方法及其在药物递送中的最新研究成果,促进了外泌体在癌症治疗中的应用。