Advances in Protein and Polypeptide Drug Analytics

⚡ 摘要

蛋白质与多肽药物分析研究进展

作者 Yuanli Mei; Hongmin Liu 期刊 Current Pharmaceutical Design 发表日期 2025 ISSN 1381-6128 DOI 10.2174/0113816128355706250626053659 类型 原创研究 (Original Research)

📄 英文摘要 English Abstract

EN

With the rapid advancement of biotechnology, protein and peptide drugs have become increasingly widespread in the medical field, yet their metabolic processes are complex and require the assistance of modern analytical methods for research. Based on the latest domestic and international research, this paper systematically reviews the application of modern analytical methods in the metabolism of protein and peptide drugs. The research focuses on key technologies such as biological activity detection, mass spectrometry, and chromatography, elaborating on their principles, characteristics, and current state of development. The aim is to provide scientific evidence and technical support for drug development, and to promote in-depth research on the metabolism of protein and peptide drugs.

📄 中文摘要 Chinese Abstract

中文
随着生物技术的快速发展,蛋白质和多肽类药物在医学领域的应用日益广泛,但其代谢过程复杂,需要借助现代分析手段进行研究。

📋 英文结构化总结 English Structured Summary

摘要整理

EN

Background:

With the rapid advancement of biotechnology, protein and peptide drugs have become increasingly widespread in the medical field, yet their metabolic processes are complex and require the assistance of modern analytical methods for research.

Methods:

Based on the latest domestic and international research, this paper systematically reviews the application of modern analytical methods in the metabolism of protein and peptide drugs. The research focuses on key technologies such as biological activity detection, mass spectrometry, and chromatography, elaborating on their principles, characteristics, and current state of development.

Results:

The paper elaborates on the principles, characteristics, and current state of development of biological activity detection, mass spectrometry, and chromatography.

Data Summary:

No quantitative results or key statistics are provided in the abstract.

Conclusions:

The aim is to provide scientific evidence and technical support for drug development, and to promote in-depth research on the metabolism of protein and peptide drugs.

Practical Significance:

The paper aims to provide scientific evidence and technical support for drug development, directly applicable to real-world medical applications.

📋 中文结构化总结 Chinese Structured Summary

中文

背景:

随着生物技术的快速发展,蛋白质和多肽类药物在医学领域的应用日益广泛,但其代谢过程复杂,需要借助现代分析手段进行研究。

方法:

本文基于国内外最新研究,系统综述了现代分析手段在蛋白质和多肽类药物代谢研究中的应用。研究重点围绕生物活性检测、质谱和色谱等关键技术,阐述了其原理、特点及发展现状。

结果:

本文详细阐述了生物活性检测、质谱和色谱等技术的原理、特点及发展现状。

数据摘要:

摘要中未提供定量结果或关键统计数据。

结论:

旨在为药物开发提供科学依据和技术支持,推动蛋白质和多肽类药物代谢的深入研究。

实际意义:

本文旨在为药物开发提供科学依据和技术支持,可直接应用于实际医学应用。