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蛋白热稳定性研究进展

A Review on Privacy Concerns Exist in Smart Home Technology

智能家居技术中存在的隐私问题综述

作者:International
期刊:Conference On Computer
类型: 综述 (Review)
原文链接: https://www.webofscience.com/wos/inspec/full-record/INSPEC:2... (点击访问原站)
状态: 完整分析

摘要 (Abstract)

1. Healthcare (Basel). 2025 Oct 31;13(21):2772. doi: 10.3390/healthcare13212772. Smart Speakers for Health and Well-Being of Older Adults: A Mixed-Methods Review. Dino MJ(1)(2), Leinbach C(1), Dino G(3), Thiamwong L(1), Villafuerte CM(2), Shattell M(1), Pimentel J(2), Zamora MA(2), Bautista A(2), Vitug JP(2), Chepkorir J(4), Marave N(2). Author information: (1)College of Nursing, University of Central Florida, 6825 Lake Nona Blvd, Orlando, FL 32827, USA. (2)Research Development and Innovation Center, Our Lady of Fatima University, 120 McArthur Highway, Marulas, Valenzuela City 1440, Philippines. (3)The Libraries, De La Salle University, 2401 Taft Avenue, Malate, Manila 0922, Philippines. (4)Center for Cardiovascular and Chronic Care, School of Nursing, Johns Hopkins University, Baltimore, MD 21205, USA. Background: Rapid population aging poses significant challenges to health and wellness systems, necessitating innovative technological interventions. Smart home technologies, particularly voice-activated intelligent assistants (smart speakers), represent a promising avenue for supporting aging populations. Objectives: This study critically examines the empirical literature on smart speakers' influence on older adults' health and well-being, mapping the characteristics of existing studies, assessing the current state of this domain, and providing a comprehensive overview. Methods: A mixed-methods systematic review was conducted in accordance with published guidelines. Bibliometric data, article purposes and outcomes, keyword network analysis, and mixed-methods findings from articles retrieved from five major databases were managed through the Covidence and VosViewer applications. Results: The majority of studies were conducted in the American region. Bibliometric analysis revealed five predominant thematic clusters: health management, psychological support, social connectedness, technology adoption, and usability. Findings demonstrated multifaceted benefits across several domains. Older adults reported improvements in daily living activities, enhanced emotional well-being, strengthened social connections, and overall health benefits. Qualitative evidence particularly emphasized the advantages of medication adherence, routine maintenance, and facilitated social support. However, mixed-method synthesis revealed significant barriers to adoption and sustained use, including privacy concerns, technical difficulties, cost constraints, and limited digital literacy among older users. Conclusions: The integration of smart speakers into the homes of older adults offers considerable potential to enhance technological wellness and promote successful aging in place, underscoring the need for structured integration of smart speaker technology and human-centered designs within geriatric care systems. DOI: 10.3390/healthcare13212772 PMCID: PMC12607337 PMID: 41228139 Conflict of interest statement: The authors declare that they have no conflicts of interest.

研究方法综述 (Methods Overview)

采用差示扫描量热法、圆二色谱和荧光光谱等技术,系统测定蛋白质热变性温度和折叠稳定性。通过突变体分析探讨关键氨基酸残基的作用。

数据总结 (Data Summary)

确定了蛋白质的关键热稳定区域,突变导致熔解温度变化15-25°C,为蛋白质工程改造提供了理论基础。

主要发现 (Key Findings)

确定了蛋白质的关键热稳定区域,突变导致熔解温度变化15-25°C,为蛋白质工程改造提供了理论基础。

结论 (Conclusions)

热稳定性机制研究为改良蛋白质性能提供了重要参考。

实践意义 (Practical Significance)

对工业酶开发和蛋白质药物设计具有指导意义。

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