The Role of Adipose Tissue and Nutrition in the Regulation of Adiponectin
脂肪组织和营养在脂联素调节中的作用
摘要 (Abstract)
<jats:p>Adipose tissue (AT), composed mainly of adipocytes, plays a critical role in lipid control, metabolism, and energy storage. Once considered metabolically inert, AT is now recognized as a dynamic endocrine organ that regulates food intake, energy homeostasis, insulin sensitivity, thermoregulation, and immune responses. This review examines the multifaceted role of adiponectin, a predominant adipokine released by AT, in glucose and fatty acid metabolism. We explore the regulatory mechanisms of adiponectin, its physiological effects and its potential as a therapeutic target for metabolic diseases such as type 2 diabetes, cardiovascular disease and fatty liver disease. Furthermore, we analyze the impact of various dietary patterns, specific nutrients, and physical activities on adiponectin levels, highlighting strategies to improve metabolic health. Our comprehensive review provides insights into the critical functions of adiponectin and its importance in maintaining systemic metabolic homeostasis.</jats:p>
实验设计与方法 (Experimental Design & Methods)
采用系统性文献综述方法，检索和分析多个数据库中的相关研究文献。
实验结果 (Experimental Results)
总结了主要研究进展、关键发现和发展趋势，识别了研究空白和未来研究方向。
数据汇总 (Data Summary)
总结了主要研究进展、关键发现和发展趋势，识别了研究空白和未来研究方向。
结论 (Conclusions)
该综述为相关领域研究提供了全面的参考框架。
实践意义 (Practical Significance)
对推动学科交叉融合和研究创新具有重要价值。