Use of DNase1L3 protein or reagent overexpressing DNase1L3 protein in preparation of medicine, synergistic tumor immunotherapy drugs and antitumor drugs for inhibiting tumor progression, delaying tumor growth, prolonging survival and treating tumor including lung cancer and/or colorectal cancer

⚡ 摘要

DNase1L3蛋白或过表达DNase1L3蛋白的试剂在制备抑制肿瘤进展、延缓肿瘤生长、延长生存期及治疗包括肺癌和/或结直肠癌的肿瘤的药物、协同肿瘤免疫治疗药物和抗肿瘤药物中的应用

期刊 Progress in the study of autophagy-related proteins affecting resistance to chemotherapeutic drugs in leukemia. 类型 原创研究 (Original Research)

📄 英文摘要 English Abstract

EN

Frontiers In Cell And Developmental Biology Leukemia is a life-threatening malignant tumor of the hematopoietic system. Currently, the main treatment modalities are chemotherapy and hematopoietic stem cell transplantation. However, increased drug resistance due to decreased sen... CYP2E1 mediated advanced oxidation protein products exacerbate acetaminophen induced drug-derived liver injury in vitro and in vivo. European Journal Of Pharmaceutical Sciences : Official Journal Of The European Federa

📄 中文摘要 Chinese Abstract

中文
白血病是一种威胁生命的造血系统恶性肿瘤。目前,主要的治疗方式是化疗和造血干细胞移植。然而,由于衰老减少导致的耐药性增加……CYP2E1介导的晚期氧化蛋白产物在体内外加剧了对乙酰氨基酚诱导的药物性肝损伤。

📋 英文结构化总结 English Structured Summary

摘要整理

EN

Background:

Leukemia is a life-threatening malignant tumor of the hematopoietic system. Currently, the main treatment modalities are chemotherapy and hematopoietic stem cell transplantation. However, increased drug resistance due to decreased sen... CYP2E1 mediated advanced oxidation protein products exacerbate acetaminophen induced drug-derived liver injury in vitro and in vivo.

Methods:

No methodology details are provided in the extracted text.

Results:

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Data Summary:

No quantitative results or key statistics are provided in the extracted text.

Conclusions:

No conclusions are provided in the extracted text.

Practical Significance:

No real-world applications are described in the extracted text.

📋 中文结构化总结 Chinese Structured Summary

中文

背景:

白血病是一种威胁生命的造血系统恶性肿瘤。目前,主要的治疗方式是化疗和造血干细胞移植。然而,由于衰老减少导致的耐药性增加……CYP2E1介导的晚期氧化蛋白产物在体内外加剧了对乙酰氨基酚诱导的药物性肝损伤。

方法:

所提取的文本中未提供方法学细节。

结果:

所提取的文本中未提供结果。

数据摘要:

所提取的文本中未提供定量结果或关键统计数据。

结论:

所提取的文本中未提供结论。

实际意义:

所提取的文本中未描述实际应用。