Agent useful as cosmetic or quasi-drug for scavenging active oxygen, inhibiting protein glycation, protein carbonylation and protein nitration, decomposing advanced glycation end products, and performing carbonylated proteolysis or nitrated proteolysis, comprises extract of Plinia cauliflora

⚡ 摘要

用作化妆品或准药物的试剂,用于清除活性氧、抑制蛋白质糖化、蛋白质羰基化和蛋白质硝化、分解晚期糖化终末产物、进行羰基化蛋白水解或硝基化蛋白水解,包含Plinia cauliflora提取物

期刊 Advances in protein kinase drug discovery through targeting gatekeeper mutations. 类型 原创研究 (Original Research)

📄 英文摘要 English Abstract

EN

Expert Opinion On Drug Discovery INTRODUCTION: Acquired resistance caused by gatekeeper mutations has become a major challenge for approved kinase inhibitors used in the clinic. Consequently, the development of new-generation inhibitors or degraders to overcome clini...

📄 中文摘要 Chinese Abstract

中文
由看门突变引起的获得性耐药已成为临床使用获批激酶抑制剂面临的主要挑战。因此,开发新一代抑制剂或降解剂以克服临床耐药问题已成为当务之急。

📋 英文结构化总结 English Structured Summary

摘要整理

EN

Background:

Acquired resistance caused by gatekeeper mutations has become a major challenge for approved kinase inhibitors used in the clinic. Consequently, the development of new-generation inhibitors or degraders to overcome clini...

Methods:

No methodology details are provided in the abstract.

Results:

No results are described in the abstract.

Data Summary:

No quantitative results or key statistics are provided in the abstract.

Conclusions:

No conclusions are described in the abstract.

Practical Significance:

No real-world applications are mentioned in the abstract.

📋 中文结构化总结 Chinese Structured Summary

中文

背景:

由看门突变引起的获得性耐药已成为临床使用获批激酶抑制剂面临的主要挑战。因此,开发新一代抑制剂或降解剂以克服临床耐药问题已成为当务之急。

方法:

摘要中未提供方法学细节。

结果:

摘要中未描述结果。

数据摘要:

摘要中未提供定量结果或关键统计数据。

结论:

摘要中未描述结论。

实际意义:

摘要中未提及实际应用。